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Combo of experimental therapies kills cancer cells

Written by: QMI Agency
 

Jan. 27, 2014

(Petrik - Fotolia.com)


 

Ottawa researchers say they’ve found a combination of experimental therapies that kills cancer cells without harming healthy tissue.

The researchers at the Children’s Hospital of Eastern Ontario (CHEO) combined a therapy that targets cancer-causing genes, called SMAC Mimetics, with a live virus or non-viral immune stimulators to create a new tumour-killing therapy.

“I firmly believe that it’s not a matter of ‘if’ this will help cancer patients — but ‘when’ this therapy becomes a standard of care,” researcher Robert Korneluk said in a press release. “The results of our combination exceeded expectations — and furthermore, no harm was done to the surrounding healthy tissue when we eradicated tumours.”

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In some cases, tumours required 10,000-times less virus to kill a cancer cell when a SMAC mimetic was added, the study found.

Korneluk said the next step will be using the therapy in clinical trials as soon as possible.

The research was published Monday in the journal Nature Biotechnology.

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