September 22, 2014
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Drug Factsheets

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Tapazole

(methimazole)

DIN (Drug Identification Number)

00015741 TAPAZOLE 5MG TABLET
02296039 TAPAZOLE 10MG TABLET

How does Tapazole work? What will it do for me?

Methimazole belongs to the class of medications called antithyroid medications. It is used to treat hyperthyroidism (overactive thyroid gland). It prevents the thyroid gland from over-producing thyroid hormone, but does not interfere with the actions of thyroid hormone. It may take weeks to months before methimazole has its full effect on the symptoms of overactive thyroid (e.g., palpitations, sweating). During this time period, other medications may be used to control these symptoms.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Tapazole?

Adults: Methimazole is taken 3 times daily, every 8 hours. The recommended starting total dose of methimazole is 15 mg daily for mild hyperthyroidism, 30 mg to 40 mg daily for moderately severe hyperthyroidism, and 60 mg daily for severe hyperthyroidism. The eventual maintenance dose is normally 5 mg to 15 mg daily.

Children: For children, the daily dose is initially 0.4 mg per kilogram of body weight, divided into 3 doses and given every 8 hours. The eventual maintenance dose is usually one-half the initial dose.

Methimazole can be taken with or without food.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor or pharmacist.

It is important to take this medication exactly as prescribed by your doctor. The 3 daily doses should be taken as close to every 8 hours as possible so that blood levels are kept as constant as possible. If you miss a dose of this medication, take it as soon as possible and check with your doctor or pharmacist.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Tapazole come in?

5 mg
Each round, white, scored tablet, marked with "J94" on one side and plain on the other, contains methimazole 5 mg. Nonmedicinal ingredients: corn starch, lactose monohydrate, magnesium stearate, and talc.

10 mg
Each round, white tablet, marked with "10" on one side and plain on the other side, contains 10 mg methimazole. Nonmedicinal ingredients: corn starch, lactose monohydrate, magnesium stearate, and talc.

Who should NOT take Tapazole?

Methimazole should not be taken by anyone who:

  • is allergic to methimazole or to any of the ingredients of the medication
  • is breast-feeding

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