November 21, 2009
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Avalide

(irbesartan - hydrochlorothiazide)

DIN (Drug Identification Number)

02241818 AVALIDE 150/12.5 MG TABLET
02241819 AVALIDE 300/12.5 MG TABLET
02280213 AVALIDE 300/25MG TABLET

How does Avalide work? What will it do for me?

This is a combination of two medications that are used to reduce high blood pressure. Irbesartan belongs to a class of medications called angiotensin II blockers and helps to lower blood pressure by relaxing blood vessels. Hydrochlorothiazide is a diuretic or "water pill" that helps control blood pressure by getting rid of excess salt and water.

This medication is most often prescribed when other medications have been found not to be effective or to have side effects, and when a person's blood pressure is stabilized on irbesartan and hydrochlorothiazide taken individually.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Avalide?

Once the dose of each component (irbesartan and hydrochlorothizide) has been determined, the combination tablets can be started.

The dose ranges from 1 tablet containing 150 mg irbesartan and 12.5 mg hydrochlorothiazide once daily to 1 tablet containing 300 mg irbesartan and 12.5 mg hydrochlorothiazide once daily. Tablets should be taken at approximately the same time each day, with or without food (but taken in the same manner each day).

If you miss a dose but remember it within 12 hours, take it as soon as possible and then go back to your regular dose. If it is more than 12 hours later than your usual dose, skip that dose and carry on as usual with your next dose. Never take a double dose to make up for a missed dose.

It is important to take this medication regularly and to follow your doctor's instructions regarding monitoring blood pressure to ensure that you receive the maximum benefit from the medication.

Irbesartan - hydrochlorothiazide should be stored at normal room temperature in a dry place (not in the bathroom).

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does Avalide come in?

150/12.5 mg
Each peach, biconvex, oval tablet, with a heart shape debossed on one side and the digits "2775" on the other, contains irbesartan 150 mg and hydrochlorothiazide 12.5 mg. Nonmedicinal ingredients: croscarmellose sodium, ferric oxide red, ferric oxide yellow, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch and silicon dioxide.

300/12.5 mg
Each peach, biconvex, oval tablet, with a heart shape debossed on one side and the digits "2776" on the other, contains irbesartan 300 mg and hydrochlorothiazide 12.5 mg. Nonmedicinal ingredients: croscarmellose sodium, ferric oxide red, ferric oxide yellow, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch and silicon dioxide.

300/25 mg
Each pink, film-coated, biconvex, oval tablet, with a heart shape debossed on one side and the digits "2788" on the other, contains irbesartan 300 mg and hydrochlorothiazide 25 mg. Nonmedicinal ingredients: black iron oxides, carnauba wax, croscarmellose sodium, ferric oxide red, ferric oxide yellow, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, silicon dioxide and titanium dioxide.

Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

Who should NOT take Avalide?

This medication should not be taken by anyone who:

  • is allergic to irbesartan, hydrochlorothiazide or any of the ingredients of the medication
  • is allergic to sulpha medications
  • pregnant
  • has anuria (no urine flow)

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