October 21, 2014

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(mycophenolate mofetil)

DIN (Drug Identification Number)


How does CellCept work? What will it do for me?

Mycophenolate mofetil belongs to the group of medications known as immunosuppressants. It is used in combination with other medications to prevent the rejection of organ transplants by suppressing the body's natural defense, the immune system. It does this by preventing the formation of a certain type of white blood cell (called lymphocytes) that would normally attack the transplanted organ.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use CellCept?

Mycophenolate mofetil is usually started as soon as possible following the organ transplant. The dose varies according to circumstances. The medication is usually given twice daily.

The 2 doses should be spaced as close to 12 hours apart as possible and at approximately the same time each day. The oral medication should be taken on an empty stomach (1 hour before or 2 hours after meals). If you vomit or have diarrhea after taking mycophenolate mofetil, always call your doctor for further direction. Do not stop taking the medication without first talking with your doctor.

You should leave the capsules and tablets in the blister packs until it is time for your dose. The capsules and tablets should be swallowed whole, and not crushed or chewed.

If using the suspension, be sure to shake the closed bottle well for about 5 seconds before each use. Do not mix the suspension with any liquid.

Avoid skin contact with damaged capsules or caplets. If any powder from any of the forms of mycophenolate mofetil should get on your skin, quickly wash with soap and water. If the medication comes in contact with your eyes, rinse them thoroughly with water.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, contact your doctor or pharmacist for instructions. Do not take a double dose to make up for a missed one.

Store mycophenolate mofetil tablets, capsules, and suspension at room temperature. Protect the tablets from light. Discard any unused portion of mycophenolate mofetil suspension 60 days after mixing.

This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does CellCept come in?

Each oblong, blue/brown, two-piece hard gelatin capsule, printed in black with "CellCept 250" on the blue cap and "Roche" on the brown body, contains mycophenolate mofetil 250 mg. Nonmedicinal ingredients: croscarmellose sodium, magnesium stearate, povidone (K-90), and pregelatinized starch; capsule shell: black iron oxide, gelatin, indigotine (FD&C Blue No. 2) Aluminum Lake, potassium hydroxide, red iron oxide, shellac, titanium dioxide, and yellow iron oxide.

Each lavender-coloured, caplet-shaped, film coated tablet, engraved with "CellCept 500" on one side and "Roche" on the other, contains mycophenolate mofetil 500 mg. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl cellulose, hydroxypropyl methylcellulose, indigotine (FD&C Blue No. 2) Aluminum Lake, iron oxide, magnesium stearate, microcrystalline cellulose, polyethylene glycol 400, povidone (K-90), and titanium dioxide.

Powder for Oral Suspension
Available as a white to off-white powder blend for reconstitution to a white to off-white fruit flavor suspension containing 200 mg/mL of mycophenolate mofetil. Each bottle of CellCept powder for oral suspension contains 35 g of MMF in a 110 g powder for oral suspension. Nonmedicinal ingredients: aspartame, citric acid, colloidal silicon dioxide, fruit flavor, methylparaben, sodium citrate, sorbitol, soybean lecithin, and xanthan gum.

Injectable solution
Each vial of sterile, white to off-white lyophilized powder for i.v. infusion contains the equivalent of mycophenolate mofetil 500 mg as the hydrochloride salt. Nonmedicinal ingredients: citric acid, polysorbate 80 (Tween), and sodium hydroxide and/or hydrochloric acid to adjust pH.

Who should NOT take CellCept?

Do not use this medication if you are allergic to mycophenolate mofetil or any ingredients of the medication.

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