September 15, 2014
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Solu-Medrol

(methylprednisolone)

DIN (Drug Identification Number)

02063727 SOLU-MEDROL ACT-O-VIAL 125MG
02063697 SOLU-MEDROL ACT-O-VIAL 1G
00036137 SOLU-MEDROL 1G POWDER VIAL
02063719 SOLU-MEDROL ACT-O-VIAL 40MG
02063700 SOLU-MEDROL ACT-O-VIAL 500MG
00030678 SOLU-MEDROL 500MG POWDER VIAL

How does Solu-Medrol work? What will it do for me?

Methylprednisolone belongs to a group of medications called corticosteroids. Corticosteroids are hormones that are produced naturally in our body, and necessary for many important bodily functions.

Methylprednisolone is a synthetic (man-made) corticosteroid medication that has been developed to imitate the actions of naturally occurring corticosteroid hormones in the body. A particularly important action of methlyprednisolone is to relieve inflammation that causes symptoms such as swelling, itching, and redness.

Symptoms of inflammation are often seen with allergic reactions such as severe allergic skin reactions, reactions to insect bites, and anaphylaxis (a severe, life-threatening allergic reaction). Other conditions and symptoms associated with inflammation can also be treated with corticosteroids. These include painful swollen joints caused by arthritis, and relief of asthma symptoms caused by inflamed breathing passages.

Methylprednisolone may also be used by people who are not able to produce enough of their own corticosteroid naturally (e.g., Addison's disease). Additional conditions that may be treated with methylprednisolone include severe skin conditions (e.g., psoriasis), certain eye conditions, ulcerative colitis, certain blood disorders, leukemia, lupus, and multiple sclerosis.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use Solu-Medrol?

The recommended dose of methylprednisolone varies widely depending on the condition being treated, response to the medication, the form of the medication being used, the age and size of the person using the medication, and individual circumstances.

The dose of the tablet form may range from 4 mg to 48 mg of methylprednisolone daily, or even much higher depending on the specific condition being treated.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Injectable medications are given either into a muscle, into a joint, or into a vein by a qualified health professional.

Taking this medication with food will help to prevent stomach upset.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose of the medication and are taking the medication once a day, but don't remember until the next day, skip the missed dose and go back to your regular dosing schedule. If you are taking the medication more than once daily, skip the missed dose and go back to your regular schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from freezing, and keep it out of the reach of children.

If you miss an appointment to receive methylprednisolone, contact your doctor as soon as possible to reschedule your appointment.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Solu-Medrol come in?

Act-O-Vials

40 mg
Each 1 mL (when mixed) contains methylprednisolone (as methylprednisolone sodium succinate) 40 mg. Nonmedicinal ingredients: monobasic sodium phosphate anhydrous, dibasic sodium phosphate dried, lactose hydrous, and bacteriostatic water for injection.

125 mg
Each 2 mL (when mixed) contains methylprednisolone (as methylprednisolone sodium succinate) 125 mg. Nonmedicinal ingredients: monobasic sodium phosphate, dibasic sodium phosphate dried, and bacteriostatic water for injection.

500 mg
Each 4 mL (when mixed) contains methylprednisolone (as methylprednisolone sodium succinate) 500 mg. Nonmedicinal ingredients: monobasic sodium phosphate anhydrous, dibasic sodium phosphate dried, and bacteriostatic water for injection.

1 g
Each 8 mL (when mixed) contains methylprednisolone (as methylprednisolone sodium succinate) 1 g. Nonmedicinal ingredients: monobasic sodium phosphate anhydrous, dibasic sodium phosphate dried, and bacteriostatic water for injection.

Vials

500 mg
Each 8 mL (when mixed) contains methylprednisolone (as methylprednisolone sodium succinate) 500 mg. Nonmedicinal ingredients: monobasic sodium phosphate anhydrous, dibasic sodium phosphate dried, and diluent.

1 g
Each 16 mL (when mixed) contains methylprednisolone (as methylprednisolone sodium succinate) 1 g. Nonmedicinal ingredients: monobasic sodium phosphate anhydrous, dibasic sodium phosphate driedg, and diluent.

Who should NOT take Solu-Medrol?

Methylprednisolone should not be used by anyone who:

  • is allergic to methylprednisolone or to any of the ingredients of the medication
  • has chickenpox
  • has Cushing's syndrome
  • has herpes simplex keratitis
  • has systemic (in the blood) fungal infections
  • has tuberculosis
  • has vaccinia (reaction to smallpox vaccine)

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