October 31, 2014
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Gravol

(dimenhydrinate)

DIN (Drug Identification Number)

02254409 GRAVOL 100MG LONG ACTING CAPLETS
00013609 GRAVOL ADULT SUPPOSITORIES 100MG
00511196 GRAVOL QUICK DISSOLVE CHEWABLE TABLET 15MG
00230197 GRAVOL LIQUID 15MG/5CC
00783595 GRAVOL SUPPOSITORIES FOR CHILDREN 25MG
02245867 GRAVOL 50MG SOFTGEL CAPSULE
00013803 GRAVOL FILMKOTE TAB 50MG/QUICK DISSOLVE CHEW TAB 50MG
00013579 GRAVOL IM 50MG/ML INJECTION

How does Gravol work? What will it do for me?

Dimenhydrinate belongs to a group of medications called antiemetics. This medication is used to prevent and treat motion sickness as well as nausea and vomiting associated with various conditions such as chemotherapy, radiation, and surgery. It is also used to treat nausea and spinning sensations (vertigo) due to Ménière's disease and other conditions that cause these symptoms.

Dimenhydrinate works to relieve or prevent nausea and vomiting by affecting the vomiting centre in the brain. Most people can expect some relief of nausea and vomiting within one hour of taking any form of dimenhydrinate. It works to relieve vertigo by affecting the brain and the inner ear.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use Gravol?

Motion sickness, nausea, vomiting, dizziness, and spinning sensation (vertigo): The usual adult dose of the tablets is 50 mg to 100 mg taken every 4 hours as needed. Do not take more than 400 mg in a 24-hour period. The dose of the long-acting form of dimenhydrinate tablets is 100 mg every 8 to 12 hours, with a maximum of 3 tablets in a 24-hour period. The usual adult dose of dimenhydrinate suppository is 50 mg to 100 mg every 6 to 8 hours as needed.

If you are taking dimenhydrinate for motion sickness, the first dose should be taken at least 30 minutes and preferably 1 to 2 hours before departure.

Pre-radiation therapy (radiation sickness): In adults, 50 mg to 100 mg of dimenhydrinate may be given as a suppository or injection, 30 to 60 minutes before receiving radiation therapy. This dose may be repeated as needed up to a maximum of 400 mg over a 24-hour period.

Surgery: To control nausea and vomiting following surgery in adults, the usual dose is 50 mg to 100 mg taken by mouth or 50 mg of injection into a muscle before surgery. After surgery, similar doses can be used up to a maximum dose of 400 mg in a 24-hour period.

Children:  Follow the dosing instructions provided to you by your doctor or pharmacist or the ones provided with the product being used. This medication should not be used for children or infants under one year old.

For children 2 to 6 years old, the dose of dimenhydrinate liquid or tablets is 15 mg to 25 mg every 6 to 8 hours as needed to a maximum of 75 mg in a 24-hour period. For the suppositories, the dose in this age group is 12.5 mg to 25 mg. Do not give more than one dose of the suppository form unless recommended by your doctor.

For children 6 to 8 years old, the dose of dimenhydrinate liquid or tablets is 25 mg to 50 mg every 6 to 8 hours as needed to a maximum of  150 mg in a 24-hour period. For the suppositories, the dose in this age group is 12.5 mg to 25 mg every 8 to 12 hours as needed.

For children 8 to 12 years old, the dose of dimenhydrinate liquid or tablets is 25 mg to 50 mg every 6 to 8 hours as needed to a maximum of  150 mg in a 24-hour period. For the suppositories, the dose in this age group is 25 mg to 50 mg every 8 to 12 hours as needed.

For children 12 years of age and older, the dose of dimenhydrinate liquid or tablets is 50 mg every 4 to 6 hours as needed to a maximum of  300 mg in a 24-hours period. For the suppositories, the dose in this age group is 50 mg every 8 to 12 hours as needed.

Chewable tablets and liquid are available for children or adults who are unable to swallow the tablets. When using the liquid, use an oral syringe to measure each dose of the liquid as it gives a more accurate measurement than household teaspoons.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as recommended by your doctor or pharmacist.

Store this medication at room temperature and keep it out of the reach of children.

This medication is available under multiple brand names and in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Gravol come in?

IM Injection
Each mL contains dimenhydrinate 50 mg. This dosage form is for IM use only, unless diluted at least 1:10 with a compatible physiological solution; i.e., sterile saline or 5% dextrose in water. Nonmedicinal ingredients: methylparaben (multidose vials only), propylene glycol, and propylparaben (multidose vials only). This medication does not contain tartrazine.

100 mg Adult Suppositories
Each white, opaque suppository contains dimenhydrinate 100 mg adult. Nonmedicinal ingredients: polyethylene glycol, silicon dioxide, and titanium dioxide. This medication does not contain gluten or tartrazine.

Filmkote Tablets 50 mg
Each round, biconvex, peach coral tablet, intagliated "GRAVOL" on one side and quadrisected on the other, contains dimenhydrinate 50 mg. Nonmedicinal ingredients: alumina, cellulose, FD&C Yellow No. 6, lactose, magnesium stearate, polyethylene glycol, silicon dioxide, starch (corn), talc, and titanium dioxide. This medication does not contain gluten or tartrazine.

Liquid
Each 5 mL of yellow, transparent, viscous liquid with a bittersweet mixed fruit flavour, contains dimenhydrinate 15 mg. Nonmedicinal ingredients: citric acid, D&C Yellow No. 10, FD&C Yellow No. 6, flavour, propylene glycol, sodium benzoate, sorbitol, and sucrose.

Children Suppositories
Each white, opaque suppository contains dimenhydrinate 25 mg. Nonmedicinal ingredients: polyethylene glycol, silicon dioxide, and titanium dioxide. This medication does not contain gluten or tartrazine.

Chewable Tablets for Children
Each round, flat, light purple, cherry-flavoured tablet, bevelled-edged intagliated with "GRAVOL 15" on one side and plain on the other side, contains dimenhydrinate 15 mg. Nonmedicinal ingredients: alumina, aspartame, cellulose, citric acid, FD&C Red No. 40, flavours, magnesium stearate, methacrylic acid copolymer, monoglycerides, polyethylene glycol, sorbitol, and starch (corn). This medication does not contain gluten or tartrazine.

Chewable Tablets for Adults
Each round, flat, light pink, orange-flavoured tablet, bevelled-edged intagliated with "GRAVOL 50" on one side and bisected on the other side, contains dimenhydrinate 50 mg. Nonmedicinal ingredients: alumina, aspartame, cellulose, citric acid, FD&C Yellow No. 6, flavours, magnesium stearate, methacrylic acid copolymer, monoglycerides, polyethylene glycol, sorbitol, and starch (corn). This medication does not contain gluten or tartrazine.

Softgel Capsules
Each pink translucent softgel capsule, printed in white "Gravol", contains dimenhydrinate 50 mg. Nonmedicinal ingredients: D&C Red No. 33, gelatin, glycerin, mannitol, methylparaben, polyethylene glycol, povidone, propylparaben, sorbitol, and water.

L/A Caplets 100 mg
Each red-white, bilayer, film-coated caplet, intagliated "GRAVOL" on one side, contains dimenhydrinate 25 mg for immediate release and dimenhydrinate 75 mg for sustained release. Nonmedicinal ingredients: butyl hydroxytoluene, calcium carbonate, calcium phosphate, FD&C Red No. 40, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyethylene oxide, and starch.

Who should NOT take Gravol?

Do not use this medication if you:

  • are allergic to dimenhydrinate or any ingredients of the medication
  • have chronic lung diseases such as chronic bronchitis or emphysema
  • have difficulty passing urine due to an enlarged prostate (prostatic hypertrophy)
  • have glaucoma

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