December 21, 2014
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Drug Factsheets

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Atacand Plus

(candesartan - hydrochlorothiazide)

DIN (Drug Identification Number)

02244021 ATACAND PLUS 16MG/12.5MG TABLET
02332922 ATACAND PLUS 32 MG/12.5 MG TABLET
02332957 ATACAND PLUS 32MG/25MG TABLET

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How does Atacand Plus work? What will it do for me?

This combination product contains 2 medications: candesartan and hydrochlorothiazide. Candesartan belongs to a family of medications known as angiotensin II receptor blockers. Hydrochlorothiazide belongs to a family of medications known as diuretics (or "water pills"). This combination medication is used to lower high blood pressure.

Candesartan works by relaxing blood vessels. Angiotensin II is a chemical that the body releases to cause the constriction (tightening up) of blood vessels. Candesartan blocks the action of angiotensin II, resulting in the relaxation of the blood vessels. This relaxation causes the blood pressure to decrease. Hydrochlorothiazide works by causing the body to get rid of excess salt and water.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

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How should I use Atacand Plus?

The usual adult dose is one tablet taken once daily at approximately the same time each day.

Treatment is started separately with candesartan and hydrochlorothiazide. Once the best dose of each individual ingredient is found, the combination medication may then be used at the appropriate strength. Candesartan - hydrochlorothiazide should not be started until the best dose of each ingredient has been determined.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Candesartan - hydrochlorothiazide may be taken with or without food. To protect the medication from unnecessary exposure to moisture and light, leave the medication in the blister package until just before you take it.

To ensure you receive the maximum benefit from the medication, it is important to take this medication regularly and to follow your doctor's instructions regarding blood pressure monitoring.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose and remember within 12 hours, take it as soon as possible and continue with your regular schedule. If more than 12 hours have passed since your usual dose time, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Atacand Plus come in?

16 mg/12.5 mg
Each oval, biconvex, peach tablet, with a score and marked "A/CS" on one side, contains candesartan cilexetil 16 mg and hydrochlorothiazide 12.5 mg. Nonmedicinal ingredients: calcium carboxymethylcellulose, hydroxypropyl cellulose, iron oxide, lactose, magnesium stearate, maize starch, and polyethylene glycol.

32 mg/12.5 mg
Each oval, biconvex, yellow tablet, with a score and marked "A/CJ"on one side, contains candesartan cilexetil 32 mg and hydrochlorothiazide 12.5 mg. Nonmedicinal ingredients: calcium carboxymethylcellulose, hydroxypropyl cellulose, iron oxide, lactose, magnesium stearate, maize starch, and polyethylene glycol.

32 mg/25 mg
Each oval, biconvex, pink tablet, with a score and marked "A/CD" on one side, contains candesartan cilexetil 32 mg and hydrochlorothiazide 25 mg. Nonmedicinal ingredients: calcium carboxymethylcellulose, hydroxypropyl cellulose, iron oxide, lactose, magnesium stearate, maize starch, and polyethylene glycol.

Who should NOT take Atacand Plus?

Do not take candesartan – hydrochlorothiazide if you:

  • are allergic to candesartan, hydrochlorothiazide, or any ingredients of this medication
  • have experienced angioedema as a reaction to any Angiotensin Receptor Blocker (ARB)
  • are allergic to sulfonamide-containing medications
  • are or plan to become pregnant
  • are breastfeeding
  • have severe kidney disease and cannot pass urine
  • have diabetes and are taking the medication alikskiren
  • have galactose intolerance or glucose malabsorption (a rare hereditary disease)

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