November 1, 2014
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Drug Factsheets

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Pennsaid

(diclofenac topical solution)

DIN (Drug Identification Number)

02247265 PENNSAID 1.5% TOPICAL SOLUTION

How does Pennsaid work? What will it do for me?

Diclofenac belongs to the class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing pain, swelling, and inflammation. The topical solution (a lotion applied to the skin) is used to relieve symptoms such as pain associated with osteoarthritis of the knee. This medication should not be used for more than 3 months.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use Pennsaid?

The usual adult dose of diclofenac topical solution is 40 drops applied to the knee 4 times daily at evenly spaced time intervals, or 50 drops applied to the knee 3 times daily at evenly-spaced time intervals.

Apply it only to clean, dry skin.

  • Squeeze 10 drops of diclofenac topical solution into the hand or directly onto the knee.
  • Spread the solution evenly around the front, back, and sides of the knee.
  • Repeat this procedure until 40 drops (if you are using it 4 times daily) or 50 drops (if you are using it 3 times daily) have been applied and the knee is completely covered.
  • To treat the other knee, repeat the procedure.
  • Allow several minutes for the medication to dry.
  • Wash your hands after applying the medication, and avoid contact with eyes or mucous membranes.

Do not apply the medication to infected, abraded, or open skin. Do not use dressings that do not breathe on top of this medication. This medication is for external use only and should not be taken by mouth. It should not be used for longer than 3 months.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Pennsaid come in?

Each mL of clear odourless liquid contains diclofenac sodium 1.5% w/w in a solution base. Nonmedicinal ingredients: dimethyl sulfoxide, glycerine, propylene glycol, ethanol, and purified water.

Who should NOT take Pennsaid?

Diclofenac topical solution should not be used by anyone who:

  • is allergic to diclofenac or to any of the ingredients of the medication
  • is a child
  • is currently taking other NSAIDs (e.g., ibuprofen, naproxen)
  • is pregnant or breast-feeding
  • currently has or has recently had inflammatory diseases of the stomach or intestines, such as a stomach or intestinal ulcer or ulcerative colitis
  • has had an allergic reaction to ASA or other anti-inflammatory medications
  • has severely impaired or deteriorating kidney function
  • has significant liver impairment or liver disease

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