September 2, 2014
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Advil Cold & Sinus

(ibuprofen - pseudoephedrine)

DIN (Drug Identification Number)

02036312 ADVIL COLD/SINUS 200MG IBUPROFEN/30MG PSEUDOEPHEDRINE TAB
02250705 ADVIL COLD/SINUS LIQUI-GELS 200MG IBUPROFEN/30MG PSEUDOEPHEDRINE CAP
02267616 ADVIL COLD/SINUS DAYTIME 200MG IBUPROFEN/30MG PSEUDOEPHEDRINE TAB

What side effects are possible with Advil Cold & Sinus?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • bloating or gas
  • constipation
  • decreased appetite
  • diarrhea
  • difficulty sleeping
  • drowsiness
  • heartburn and indigestion
  • lightheadedness
  • nausea
  • nervousness
  • restlessness
  • stomach cramps
  • vomiting
  • weakness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blurred vision or other eye symptoms
  • dizziness
  • fast, pounding heartbeat (palpitations)
  • ringing in the ears
  • skin rash
  • swelling
  • weight gain

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • black, tarry stools
  • blood in vomit
  • symptoms of a severe allergic reaction (difficulty breathing, hives, swelling of the mouth or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Advil Cold & Sinus?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Bladder problems: This medication may cause bladder pain, painful or difficult urination, or increased frequency of urination. If these symptoms occur without an explanation (e.g., infection), stop taking this medication and contact your doctor.

Bleeding problems: If you have bleeding problems (e.g., hemophilia) or are taking anticoagulants (e.g., warfarin), you should not take this medication, unless recommended by your doctor.

Drowsiness and dizziness: This medication can cause drowsiness and dizziness that may affect your ability to drive or operate machinery safely. If this medication affects you this way, do not perform these tasks.

Fluid retention: This medication can cause fluid retention. If you have heart failure or high blood pressure, fluid retention may worsen your condition. If you notice worsening of the symptoms of heart failure or your blood pressure increases while taking this medication, contact your doctor.

General: If your symptoms do not improve contact your doctor. Do not use this medication for longer than 3 days for a fever or 5 days for pain or cold symptoms without consulting your doctor or pharmacist.

Kidney problems: This medication may cause kidney problems. If you have reduced kidney function, heart failure, are taking diuretics (e.g., hydrochlorothiazide, furosemide), or are a senior, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Medical conditions: If you have heart disease, high blood pressure, thyroid disease, narrow angle glaucoma, diabetes, or difficulty in urination due to enlargement of the prostate gland, you should not take this medication unless directed by a doctor.

Stomach ulcers and bleeding: Ibuprofen may cause ulcers or bleeding in the stomach or intestines. If you experience black, tarry stools, vomit that looks like coffee grounds, or stomach pain while taking this medication, contact your doctor immediately. If you have a history of stomach problems, discuss with your doctor or pharmacist how this medication may affect your medical condition and whether any special monitoring is needed.

Pregnancy: This medication should not be used during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication should not be used while breast-feeding.

Children: The caplets and liquid-gels should not be given to children less than 12 years old. The liquid form of the medication should not be given to children less than 6 years old.

Seniors: Seniors may be more likely to experience side effects from this medication.

What other drugs could interact with Advil Cold & Sinus?

There may be an interaction between ibuprofen - pseudoephedrine and any of the following:

  • acetaminophen
  • acetylsalicylic acid (ASA)
  • alcohol
  • anticoagulants (e.g., heparin, warfarin)
  • blood pressure medications (e.g., atenolol, ramipril, amlodipine)
  • chlorpromazine
  • cholestyramine
  • colestipol
  • corticosteroids (e.g., prednisone)
  • cyclosporine
  • diabetes medications (e.g., glyburide and insulin)
  • digoxin
  • diuretics (e.g., hydrochlorothiazide, furosemide)
  • herbs that may increase the risk of bleeding (e.g., cat's claw, dong quai, feverfew, garlic, ginger)
  • lithium
  • MAO inhibitors (i.e., moclobemide, phenelzine)
  • methotrexate
  • other cold and allergy medications
  • other NSAIDs (e.g., naproxen, diclofenac, ketorolac)
  • pemetrexed
  • phenytoin
  • pindolol
  • probenecid
  • thyroxine
  • SNRIs (e.g., desvenlafaxine, duloxetine, venlafaxine)
  • sodium salicylate
  • SSRIs (e.g., citalopram, escitalopram, fluoxetine, paroxetine, sertraline)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, and street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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