February 9, 2010
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Apo-Indomethacin

(indomethacin)

DIN (Drug Identification Number)

00611158 APO-INDOMETHACIN 25MG CAPSULE
00611166 APO-INDOMETHACIN 50MG CAPSULE

How does Apo-Indomethacin work? What will it do for me?

Indomethacin belongs to the class of medications known as nonsteroidal anti-inflammatories (NSAIDs). It works by reducing pain, swelling, and inflammation. Indomethacin is used for the relief of mild to moderately severe pain accompanied by inflammation. It can be used for people with conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and gout.

Your doctor may choose to use this medication for conditions other than the ones listed here. If you're unsure why you are taking this medication, contact your doctor.

How should I use Apo-Indomethacin?

When used on a regular basis, the recommended adult starting dose of indomethacin capsules is 25 mg two or three times a day. Your doctor will gradually increase the dose until the best results are achieved with the least amount of side effects. The maximum recommended daily dose of indomethacin is 200 mg. Indomethacin should always be taken with food or antacids to reduce stomach upset.

The recommended dose of indomethacin suppositories is 100 mg to 200 mg daily. Doses higher than 100 mg must be given in two divided doses.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is very important that this medication be taken on a regular schedule exactly as prescribed by your doctor. If you miss a dose of this medication take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and carry on with your regular schedule. Do not double-up on doses.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does Apo-Indomethacin come in?

25 mg
Each blue and white no. 3 capsule, identified APO 25, contains indomethacin 25 mg. Nonmedicinal ingredients: cornstarch, lactose monohydrate, stearic acid and talc; capsule shell: D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin and titanium dioxide; edible black ink: D&C Yellow No. 10 aluminum lake, FD&C Blue No. 1 aluminum lake, FD&C Blue No. 2 aluminum lake, FD&C Red No. 40 aluminum lake, pharmaceutical glaze and synthetic black iron oxide; may contain n-butyl alcohol, propylene glycol and SDA-3A alcohol.

50 mg
Each blue and white no. 1 capsule, identified APO 50, contains indomethacin 50 mg. Nonmedicinal ingredients: cornstarch, lactose monohydrate, stearic acid and talc; capsule shell: D&C Red No. 28, FD&C Blue No. 1, FD&C Red No. 40, gelatin and titanium dioxide; edible black ink: D&C Yellow No. 10 aluminum lake, FD&C Blue No. 1 aluminum lake, FD&C Blue No. 2 aluminum lake, FD&C Red No. 40 aluminum lake, pharmaceutical glaze and synthetic black iron oxide; may contain n-butyl alcohol, propylene glycol and SDA-3A alcohol.

Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

Who should NOT take Apo-Indomethacin?

Indomethacin should not be taken by anyone who:

  • currently has or recently had inflammatory diseases of the stomach and intestines such as stomach or intestinal ulcer or ulcerative colitis
  • is currently taking other NSAIDs
  • is or may be allergic to indomethacin or any of the ingredients of the medication
  • has had an allergic reaction to ASA or other anti-inflammatory medications

Suppositories should not be used by anyone who:

  • has any inflammatory lesions of the rectum or anus
  • has recently had rectal or anal bleeding

Indomethacin is not safe for use by children.

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