December 17, 2014
ABCDEFGHIJKLMNOPQRSTUVWXYZ

Drug Factsheets

 Health Home >> Medications 

Abilify

(aripiprazole)

DIN (Drug Identification Number)

02322374 ABILIFY 2MG TABLET
02322382 ABILIFY 5MG TABLET
02322390 ABILIFY 10MG TABLET
02322404 ABILIFY 15MG TABLET
02322412 ABILIFY 20MG TABLET
02322455 ABILIFY 30MG TABLET

What side effects are possible with Abilify?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • anxiety
  • constipation
  • dizziness
  • drowsiness
  • extrapyramidal symptoms (abnormal body movements, restlessness, shaking, or stiffness)
  • headache
  • heartburn or indigestion
  • lightheadedness
  • nausea
  • restlessness
  • skin rash (on its own)
  • tremors
  • trouble sleeping
  • vomiting
  • weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • difficulty swallowing
  • dizziness when rising from a sitting or lying position
  • muscle twitching or abnormal movements of the face or tongue
  • signs of a blood clot in blood vessels, such as chest pain, abnormal heart rhythm, pain and swelling in one leg muscle
  • symptoms of an infection (e.g., sore throat, fever, chills, cough)
  • symptoms of high blood sugar (excessive thirst or hunger, excessive urination, weight loss, tiredness)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • long-lasting (greater than 4 hours) and painful erection of the penis
  • seizures
  • signs of stroke (e.g., sudden weakness or numbness of the face, arms, or legs, and speech or vision problems)
  • symptoms of a severe allergic reaction (hives; difficulty breathing; difficulty swallowing; swelling of the face, mouth, throat, or tongue)
  • very stiff muscles with high fever, rapid or irregular heartbeat, sweating, confusion, or reduced consciousness

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Abilify?

Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take this medication.

Abnormal heart rhythms: This medication can cause an abnormal heart rhythm problem called QT prolongation. If you have a history of QT prolongation, slow or irregular heart beat, irregular heart rhythm, heart failure, heart attack, heart disease, taking other medications known to cause QT prolongation, or a family history of sudden cardiac death at less than 50 years of age, discuss with your doctor how this medication may affect your medical condition, or how your medical condition may affect the dosing and effectiveness of this medication. Your doctor will perform tests at regular intervals to monitor for any changes in your heart rhythm.

Body temperature: Aripiprazole, like other antipsychotic medications, may interfere with your body's ability to regulate body temperature. People who exercise vigorously, who are exposed to extreme heat, are dehydrated, or are taking anticholinergic medications (e.g., benztropine, oxybutynin) are more at risk. Contact your doctor as soon as possible if you feel very hot and are unable to cool.

Take care to avoid overheating during strenuous exercise or in hot temperatures, and avoid becoming dehydrated by drinking enough fluids.

Diabetes: Aripiprazole may increase blood sugar for people with diabetes or those who are at risk for diabetes. If you have diabetes, monitor your blood sugar frequently as recommended by your doctor. If you experience symptoms of high blood sugar (e.g., increased urination, increased thirst, increased eating, and weakness) while taking this medication, contact your doctor.

Drowsiness/reduced alertness: Aripiprazole may cause drowsiness or lightheadedness, which could interfere with your ability to do activities requiring alertness, such as driving a car. Avoid these activities if the medication affects you in this way. Avoid alcohol while taking aripiprazole as it may increase your drowsiness.

Lactose: This medication contains lactose and should not be taken by people with rare problems of galactose intolerance or problems absorbing glucose or galactose.

Low blood pressure: Some people taking aripiprazole may experience sudden blood pressure drops when getting up from a sitting or lying position. These blood pressure drops could lead to dizziness, lightheadedness, and falls. If you experience this problem, try getting up more slowly. If it persists or if you faint, contact your doctor.

If you have or have had heart disease, stroke, "mini-stroke", or are at risk of experiencing low blood pressure (e.g., dehydration, taking medications for high blood pressure), discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Neuroleptic malignant syndrome (NMS): This medication may cause a potentially fatal reaction called neuroleptic malignant syndrome (NMS). If you develop symptoms of NMS, such as muscle stiffness, fever, confusion, sweating, or irregular heartbeat, stop taking this medication and seek immediate medical attention.

Seizures: Seizures have occurred in people taking aripiprazole. If you have a history of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. If you experience a seizure while taking this medication, get immediate medical attention.

Seniors: There may be a higher risk of deaths associated with the use of aripirazole by elderly people with dementia. Talk to your doctor about the risks and benefits of using this medication

Swallowing problems: People taking aripiprazole may have difficulty swallowing. Seniors and people on other antipsychotic medications should be closely monitored by their doctor for swallowing problems while they are using this medication. If you experience difficulty swallowing while taking this medication, contact your doctor.

Tardive dyskinesia: People taking this medication may develop tardive dyskinesia, a syndrome of uncontrolled body movements. This syndrome may be irreversible. If you develop uncontrolled or unusual body movements, contact your doctor as soon as possible.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking aripiprazole, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of this medication have not been established for children less than 13 years of age. Aripiprazole may be used by adolescents 15 years and older to treat schizophrenia. It may also be used by adolescents 13 years and older to treat bipolar disorder. The use of aripiprazole to aid in the treatment of depression has not been studied for this age group and is therefore, not recommended. Movement disorders such as tardive dyskinesia are more likely to occur in this age group. Report any unusual body movements to your doctor as soon as possible.

Seniors: Seniors taking this medication for dementia-related psychosis have a higher risk of strokes and death compared to seniors who are not taking the medication. Aripiprazole is not approved or recommended for seniors for this purpose.

What other drugs could interact with Abilify?

There may be an interaction between aripiprazole and any of the following:

  • abiraterone
  • amantadine
  • amiodarone
  • amphetamines (e.g., dextroamphetamine, methylphenidate)
  • antiemetics (e.g., dolasetron, ondansetron)
  • aprepitant
  • atazanavir
  • atomoxetine
  • azelastine
  • "azole" antifungals (e.g., fluconazole, ketoconazole, voriconazole)
  • bosentan
  • bromocriptine
  • buprenorphine
  • bupropion
  • carbamazepine
  • celecoxib
  • cholecalciferol
  • chloroquine
  • cisapride
  • cyclobenzaprine
  • cyclosporine
  • cyproterone
  • dasatinib
  • deferasirox
  • delavirdine
  • dexamethasone
  • dextromethorphan
  • dihydroergotamine
  • disopyramide
  • domperidone
  • donepezil
  • droperidol
  • entacapone
  • ergonovine
  • estrogens
  • flecanide
  • gabapentin
  • galantamine
  • HIV non-nucleoside reverse transcriptase inhibitors (e.g., delaviridine, efavirenz, etravirine, nevirapine)
  • imatinib
  • isoniazid
  • levodopa
  • lithium
  • macrolide antibiotics (e.g., azithromycin, clarithromycin, erythromycin)
  • MAO inhibitors (e.g., moclobemide, selegiline, tranylcypromine, phenelzine)
  • medications used to treat high blood pressure (e.g., acebutolol, diltiazem, irbesartan)
  • medroxyprogesterone
  • meperidine
  • metoclopramide
  • metronidazole
  • mifepristone
  • modafinil
  • nefazodone
  • other medications that cause drowsiness, such as:
    • alcohol
    • anti-anxiety medications (e.g., lorazepam, diazepam)
    • antihistamines (e.g., diphenhydramine, doxylamine, hydroxyzine)
    • antipsychotic medictions (e.g., chlorpromazine, haloperidol, olanzepine, quetiapine, risperidone)
    • general anesthetics (medications used to put people to sleep before surgery)
    • narcotics (e.g., codeine, morphine, oxycodone)
    • tricyclic antidepressants (e.g., amitriptyline, imipramine)
  • oxybutynin
  • phenobarbital
  • phenytoin
  • pioglitazone
  • pramipexole
  • prednisone
  • primidone
  • protease inhibitors (e.g., lopinavir, ritonavir, saquinavir)
  • proton pump inhibitors (PPIs; e.g., lansoprazole, omeprazole)
  • quinine
  • quinidine
  • ranitidine
  • rifabutin
  • rifampin
  • rivastigmine
  • ropinirole
  • selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, duloxetine, fluoxetine, paroxetine, sertraline)
  • "statin" anti-cholesterol medications (e.g., atorvastatin, simvastatin)
  • St. John's Wort
  • tetracycline
  • ticlopidine
  • tramadol
  • trazodone
  • "triptan" migraine medications (e.g., naratriptan, sumatriptan)
  • tryptophan
  • vandetanib
  • vemurafenib
  • yohimbine
  • zafirlukast

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Previous | 1 | 2 | 


Did you find what you were looking for on our website? Please let us know.

Ad

The contents of this site are for informational purposes only and are meant to be discussed with your physician or other qualified health care professional before being acted on. Never disregard any advice given to you by your doctor or other qualified health care professional. Always seek the advice of a physician or other licensed health care professional regarding any questions you have about your medical condition(s) and treatment(s). This site is not a substitute for medical advice.

© 1996 - 2014 MediResource Inc. - MediResource reaches millions of Canadians each year.