September 1, 2014
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Drug Factsheets

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Frisium

(clobazam)

DIN (Drug Identification Number)

02221799 FRISIUM 10MG TABLET

How does Frisium work? What will it do for me?

Clobazam belongs to the class of medications known as benzodiazepines. It is used to treat certain seizure disorders. It is used as an add-on to other antiseizure medications when extra treatment for control of seizures is needed.

Seizures are caused by uncontrolled firing of neurons in the brain (also referred to as increased electrical activity in the brain). This medication works by reducing the rate of firing of these neurons.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Frisium?

The recommended adult dose of clobazam ranges from 5 mg to 80 mg daily, as directed by your doctor, taken in 1 or 2 doses with or without food. Doses up to 30 mg daily may be taken as a single daily dose. Higher doses must be split into 2 daily doses. The dose is usually started at 5 mg to 15 mg daily and increased gradually as needed. For children 2 to 16 years, the starting dose should be 5 mg daily, increased gradually to a maximum of 40 mg per day. For children younger than 2 years, the starting dose is based on body weight. If you have reduced liver or kidney function, your doctor may recommend a lower dose.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Frisium come in?

Each white, uncoated, round tablet, scored on one side with "B" marked above the score line and "GL" below the score line, and the other side marked with a logo, contains clobazam 10 mg. Nonmedicinal ingredients: lactose, cornstarch, talc, colloidal silicon dioxide, and magnesium stearate.

Who should NOT take Frisium?

Do not take this medication if you:

  • are allergic to clobazam or any ingredients of this medication
  • are allergic to other benzodiazepines (e.g., diazepam, lorazepam)
  • are breast-feeding
  • are in the first 3 months of pregnancy
  • have a history of drug or alcohol dependence
  • have acute narrow-angle (closed-angle) glaucoma
  • have myasthenia gravis
  • have severe breathing problems or sleep apnea
  • have severe liver impairment

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