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Apo-Amitriptyline
(amitriptyline)-
In this factsheet:
- How does Apo-Amitriptyline work? What will it do for me?
- How should I use Apo-Amitriptyline?
- What form(s) does Apo-Amitriptyline come in?
- Who should NOT take Apo-Amitriptyline?
- What side effects are possible with Apo-Amitriptyline?
- Are there any other precautions or warnings for Apo-Amitriptyline?
- What other drugs could interact with Apo-Amitriptyline?
DIN (Drug Identification Number)
| 00335053 | APO-AMITRIPTYLINE 10MG TABLET |
| 00335061 | APO-AMITRIPTYLINE 25MG TABLET |
| 00335088 | APO-AMITRIPTYLINE 50MG TABLET |
| 00754129 | APO-AMITRIPTYLINE 75MG TABLET |
How does Apo-Amitriptyline work? What will it do for me?
Amitriptyline belongs to a family of medications known as tricyclic antidepressants. It is used to treat depression. It works in the central nervous system (CNS) to elevate the mood of people with depression. It is believed to work by keeping the balance of natural chemicals (called neurotransmitters) in the body: serotonin and norepinephrine.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use Apo-Amitriptyline?
The usual starting dose of amitriptyline for depression in adults is 25 mg to 50 mg per day. The dose of amitriptyline is usually started low and increased slowly, as prescribed by your doctor, until the medication is at a dose that is appropriate and effective. The usual maintenance dose of amitriptyline for adults ranges from 50 mg to 100 mg per day in divided doses. For some people, the daily dose can be given as a single dose, preferably at bedtime.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
What form(s) does Apo-Amitriptyline come in?
10 mg
Each round, blue, biconvex, film-coated tablet, identified "10", contains amitriptyline HCl 10 mg. Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, FD&C Blue No. 1 Aluminum Lake, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol (carbowax), and titanium dioxide.
25 mg
Each round, yellow, biconvex, film-coated tablet, identified "25", contains amitriptyline HCl 25 mg. Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, D&C Yellow No. 10 Aluminum Lake, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol (carbowax), and titanium dioxide.
50 mg
Each round, brown, biconvex, film-coated tablet, identified "50", contains amitriptyline HCl 50 mg. Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, FD&C Blue No. 2, FD&C Yellow No. 6, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol (carbowax), and titanium dioxide.
75 mg
Each round, orange, biconvex, film-coated tablet, identified APO over "75", contains amitriptyline HCl 75 mg. Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, FD&C Yellow No. 6, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol (carbowax), and titanium dioxide.
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take Apo-Amitriptyline?
Amitriptyline should not be taken by anyone who:
- is allergic to amitriptyline or to any of the ingredients of the medication
- is taking an MAO inhibitor (e.g., phenelzine, tranylcypromine) or has taken one in the past 14 days
- has a history of an allergic reaction to any of the antidepressants from the tricyclic antidepressant family (e.g., nortriptyline, desipramine, imipramine)
- has acute congestive heart failure
- has recently had a heart attack
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