November 24, 2014
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Drug Factsheets

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Anusol HC

(hydrocortisone - zinc sulfate)

DIN (Drug Identification Number)

00505773 ANUSOL-HC 0.5% OINTMENT
00476285 ANUSOL-HC 10MG SUPPOSITORIES

What side effects are possible with Anusol HC?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • dizziness
  • thin, fragile skin
  • unusual weight gain

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • burning and itching of skin
  • chills
  • diarrhea
  • false sense of well-being
  • fever
  • infection
  • painful, red, or itchy pus-containing blisters in hair follicles
  • rectal bleeding, burning, dryness, itching, or pain not present before treatment
  • sensation of pins and needles
  • stabbing pain

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Anusol HC?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Tell all health professionals involved in your care that you have been using topical (skin-applied) corticosteroids.

Adverse effects: Although side effects from using this medication are uncommon and should not occur with ordinary use, there have been rare instances of sensitization, irritation, and failure of therapeutic response. Stop using this medication and call a doctor if you experience irritation, an allergic reaction, or sensitization.

Bleeding from rectum: Call your doctor right away if you notice bleeding from the rectum.

Infection: Topical corticosteroids may increase the risk of developing a skin infection. Contact your doctor if you notice any increased redness, swelling, heat, or pain around the area where the medication is applied, as these are possible signs of infection.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using this medication, contact your doctor immediately.

Breast-feeding: This medication may pass into breast milk. If you are a breast-feeding mother and are using this medication, talk to your doctor about whether you should continue breast-feeding.

What other drugs could interact with Anusol HC?

There may be an interaction between hydrocortisone - zinc sulfate and any of the following:

  • other medications that are being applied or used rectally
  • other topical medications that contain corticosteroids or that have irritating effects

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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