April 20, 2014
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Drug Factsheets

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Pantoloc

(pantoprazole)

DIN (Drug Identification Number)

02241804 PANTOLOC 20MG TABLET
02229453 PANTOLOC 40MG TABLET

How does Pantoloc work? What will it do for me?

Pantoprazole belongs to the family of medications called proton pump inhibitors (PPIs). Proton pump inhibitors are used to treat conditions such as stomach ulcers, intestinal ulcers, and gastroesophageal reflux disease (GERD, reflux esophagitis) by reducing the amount of acid the stomach produces. Pantoprazole is also sometimes used along with antibiotics to treat stomach ulcers that are caused by bacteria known as H. pylori.

Pantoprazole can also be used to treat or reduce the risk of stomach ulcers due to medications known as nonsteroidal anti-inflammatory drugs (NSAIDs), which irritate the stomach.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Pantoloc?

The recommended dose of pantoprazole to treat reflux esophagitis is 40 mg once daily in the morning for 4 to 8 weeks. Treatment may be maintained at a dose of 20 mg to 40 mg once daily.

To treat GERD or heartburn, the recommended dose is 40 mg once daily for up to 4 weeks.

To prevent stomach ulcers associated with NSAID use, the dose is 20 mg once daily in the morning.

To treat duodenal (intestinal) ulcers, the recommended dose is 40 mg once daily in the morning for 2 to 4 weeks.

To treat gastric (stomach) ulcers, the recommended dose is 40 mg once daily in the morning for 4 to 8 weeks.

To treat duodenal (intestinal) ulcers caused by H. pylori in adults, the dose of pantoprazole is 40 mg twice daily taken with amoxicillin 1,000 mg twice daily and clarithromycin 500 mg twice daily, or pantoprazole 40 mg twice daily taken with metronidazole 500 mg twice daily and clarithromycin 500 mg twice daily. The usual duration of this treatment is 7 days.

Do not chew or crush the tablets, and take them with a glass of water in the morning either before, during, or after breakfast.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Pantoloc come in?

20 mg
Each enteric-coated, yellow, oval, biconvex tablet, marked "P20" on one side, contains pantoprazole 20 mg (pantoprazole sodium sesquihydrate 22.6 mg). Nonmedicinal ingredients: anhydrous sodium carbonate, calcium stearate, crospovidone, ferric oxide, mannitol, methylhydroxypropyl cellulose, poly (ethylacrylate, methacrylic acid), polysorbate 80, polyvidone, propylene glycol, sodium lauryl sulfate, titanium dioxide, and triethyl citrate.

40 mg
Each enteric-coated, yellow, oval, biconvex tablet, marked "P40" on one side, contains pantoprazole 40 mg (pantoprazole sodium sesquihydrate 45.1 mg). Nonmedicinal ingredients: anhydrous sodium carbonate, calcium stearate, crospovidone, ferric oxide, mannitol, methylhydroxypropyl cellulose, poly (ethylacrylate, methacrylic acid), polysorbate 80, polyvidone, propylene glycol, sodium lauryl sulfate, titanium dioxide, and triethyl citrate.

Who should NOT take Pantoloc?

Pantoprazole should not be taken by anyone who:

  • is allergic to pantoprazole or to any of the ingredients of the medication
  • is also using the medication atazanavir

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