July 25, 2014
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Olestyr

(cholestyramine resin)

DIN (Drug Identification Number)

02210320 OLESTYR REGULAR 4G/9G POWDER FOR SUSPENSION
00890960 OLESTYR LIGHT 4G/5G POWDER FOR SUSPENSION

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To find out your risk of a stroke in the next 10 years, use the stroke risk assessment calculator.

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How does Olestyr work? What will it do for me?

Cholestyramine resin belongs to the class of medications known as bile acid sequestrants. When used along with changes to diet and exercise, this medication helps to reduce cholesterol levels in the blood. It works by binding to cholesterol-like substances called bile acids in the intestines and preventing them from being absorbed into the body.

Cholestyramine resin may be used for symptomatic control of bile-induced diarrhea due to short bowel syndrome and may also be used to relieve itchiness associated with partial blockage of bile ducts.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Olestyr?

The recommended dose of cholestyramine resin is 4 g (1 packet) 1 to 6 times daily depending on circumstances.

The powder must be mixed with water (120 mL to 180 mL for the regular powder and 60 mL to 90 mL for the "light" powder) or other fluids (milk, fruit juice, or other non-carbonated beverage). It may also be mixed with watery soups or pulpy fruits with a high moisture, content such as applesauce or crushed pineapple.

Other medications should be taken at least one hour before or 4 to 6 hours after cholestyramine resin. Cholestyramine should never be taken in its dry form. The colour of cholestyramine resin may vary somewhat from batch to batch but this does not affect the performance of the medication.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Olestyr come in?

Light/Orange and Lemon-Lime Flavours
Each 5 g dose of powder contains cholestyramine resin 4 g (dried basis). Nonmedicinal ingredients: aspartame, citric acid, colloidal silicon dioxide, and propylene glycol alginate; lemon-lime flavour: D&C Yellow No. 10 and natural lemon-lime flavour; orange flavour: FD&C Yellow No. 6 and natural orange flavour. Sugar-free.

Regular
Each 9 g dose of powder contains cholestyramine resin 4 g (dried basis). Nonmedicinal ingredients: citric acid, colloidal silicon dioxide, D&C Yellow No. 10 Aluminum Lake, FD&C Yellow No. 6, natural and artificial orange flavour, propylene glycol alginate, and sucrose. Sodium- and tartrazine-free.

Who should NOT take Olestyr?

Cholestyramine resin should not be taken by anyone who:

  • is allergic to cholestyramine resin or to any of the ingredients of the medication
  • has bile ducts that are completely blocked

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