November 22, 2014
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Drug Factsheets

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Tridural

(tramadol extended release)

DIN (Drug Identification Number)

02296381 TRIDURAL 100 MG TABLET (EXTENDED RELEASE)
02296403 TRIDURAL 200 MG TABLET (EXTENDED RELEASE)
02296411 TRIDURAL 300 MG TABLET (EXTENDED RELEASE)

How does Tridural work? What will it do for me?

Tramadol belongs to a group of medications called opioid analgesics. It is used to manage severe pain for people who need several days or more of pain control. It decreases pain by acting on the central nervous system.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Tridural?

The usual starting dose of tramadol extended release is 100 mg once every 24 hours. Your doctor may gradually increase the dose by 100 mg every 2 to 5 days, up to a maximum of 300 mg every 24 hours.

The medication may be taken with or without food, but it should be taken consistently (i.e., either always with food or always without food) and with a glass of water. The tablets should be swallowed whole and must not be broken, chewed, or crushed. Breaking the tablets may cause too much medication to be absorbed into the body at one time and may be fatal.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Do not stop taking this medication without talking with your doctor. If this medication is stopped suddenly, you may experience withdrawal symptoms such as anxiety, sweating, trouble sleeping, shakiness, nausea, tremors, diarrhea, or hallucinations.

It is important to that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Tridural come in?

100 mg
Each white, bevelled-edge, round, biconvex tablet, plain on one side and printed "LP 100" in black ink on the other, contains tramadol hydrochloride 100 mg. Nonmedicinal ingredients: ammonium hydroxide, colloidal silicon dioxide, Contramid (modified starch), hydrogenated vegetable oil, iron oxide black, isopropyl alcohol, magnesium stearate, n-butyl alcohol, polyvinyl acetate, povidone, propylene glycol, shellac glaze, sodium lauryl sulfate, and xanthan gum.

200 mg
Each white, bevelled-edge, round, biconvex tablet, plain on one side and printed "LP 200" in black ink on the other, contains tramadol hydrochloride 200 mg. Nonmedicinal ingredients: ammonium hydroxide, colloidal silicon dioxide, Contramid (modified starch), hydrogenated vegetable oil, iron oxide black, isopropyl alcohol, magnesium stearate, n-butyl alcohol, polyvinyl acetate, povidone, propylene glycol, shellac glaze, sodium lauryl sulfate, and xanthan gum.

300 mg
Each white, bevelled-edge, round, biconvex tablet, plain on one side and printed "LP 300" in black ink on the other, contains tramadol hydrochloride 300 mg. Nonmedicinal ingredients: ammonium hydroxide, colloidal silicon dioxide, Contramid (modified starch), hydrogenated vegetable oil, iron oxide black, isopropyl alcohol, magnesium stearate, n-butyl alcohol, polyvinyl acetate, povidone, propylene glycol, shellac glaze, sodium lauryl sulfate, and xanthan gum.

Who should NOT take Tridural?

Do not take tramadol if you:

  • are allergic to tramadol or any ingredients of the medication
  • are allergic to other opioid medications (e.g., codeine, morphine)
  • are intoxicated with alcohol or other medications that can depress breathing and consciousness - such as hypnotics, other opioids (e.g., codeine or morphine), or psychotropic medications (certain medications for mental health conditions)
  • are breast-feeding or pregnant
  • are treating pain caused by surgery
  • are experiencing acute asthma or other obstructive airway disease
  • are experiencing acute respiratory depression
  • have a blockage or narrowing of the gastrointestinal tract
  • have a head injury, brain tumour, or increased pressure inside the head or spinal cord
  • have any condition that reduces the movement of masses through the digestive tract, such as ileus
  • have mild pain, pain that comes and goes, or pain which can be treated with other pain medications
  • have severe kidney function impairment
  • have severe liver function impairment
  • have taken monoamine oxidase (MAO) inhibitor medications (e.g., phenelzine, tranylcypromine) within the last 14 days

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