October 31, 2014
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Drug Factsheets

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Kivexa

(abacavir - lamivudine)

DIN (Drug Identification Number)

02269341 KIVEXA 600MG / 300MG TABLET

How does Kivexa work? What will it do for me?

This combination product contains 2 medications: abacavir and lamivudine. Abacavir and lamivudine belong to a class of medications known as nucleoside reverse transcriptase inhibitors (NRTIs). Reverse transcriptase is a part of HIV that is needed to infect cells in order to make more virus. Abacavir and lamivudine prevent reverse transcriptase from working properly.

The combination of these medications into a single product creates a simpler alternative to taking these medications individually.

Abacavir - lamivudine is used to help prevent the human immunodeficiency virus (HIV) from reproducing. The HIV virus is the virus responsible for acquired immune deficiency syndrome (AIDS). HIV infection destroys CD4 (T) cells, which are important to the immune system. The immune system helps fight infections.

This medication does not cure AIDS and does not prevent it from being spread to others. It is used in combination with other anti-HIV medications to slow further growth or reproduction of HIV and seems to slow down the destruction of the immune system. This may help to delay the development of problems such as infections related to AIDS or HIV disease.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Kivexa?

The usual recommended dose of abacavir - lamivudine for adults is one tablet (600 mg of abacavir and 300 mg of lamivudine) once daily.

This medication may be taken with food or on an empty stomach.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Kivexa come in?

Each orange, film-coated, modified capsule-shaped tablet, debossed with "GS FC2" on one side and plain on the other side, contains abacavir 600 mg as abacavir sulfate and lamivudine 300 mg. Nonmedicinal ingredients: FD&C Yellow No. 6 Aluminum Lake, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol 400, polysorbate 80, sodium starch glycolate, and titanium dioxide.

Who should NOT take Kivexa?

Do not take abacavir - lamivudine if you:

  • are allergic to abacavir, lamivudine, or any ingredients of the medication
  • have had a hypersensitivity reaction to abacavir or any medication containing abacavir
  • have reduced liver function

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