September 16, 2014
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Drug Factsheets

 Health Home >> Medications 

Flagyl

(metronidazole)

DIN (Drug Identification Number)

01926861 FLAGYL 10% VAGINAL CREAM
01926853 FLAGYL 500MG CAPSULE

What side effects are possible with Flagyl?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • change in taste sensation
  • confusion
  • constipation
  • darker urine
  • diarrhea
  • dizziness or lightheadedness
  • dryness of mouth
  • headache
  • heartburn
  • loss of appetite
  • nausea
  • stomach pain or cramps
  • unpleasant or sharp metallic taste
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • any vaginal irritation, discharge, or dryness not present before use of this medicine
  • fever or unexpected infections
  • mood or other mental changes
  • skin rash, redness, or itching
  • vision changes

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • convulsions (seizures)
  • difficulty coordinating body movement
  • extreme sensitivity to bright light
  • numbness, tingling, pain, or weakness in hands or feet
  • pain
  • signs of a serious allergic reaction ( e.g.,difficulty breathing, itchyskin rash, swelling of face or throat, wheezing)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • stiff neck along with a headache

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Flagyl?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Alcohol: A severe set of side effects including nausea, vomiting, and rapid heartbeat may occur if you drink alcohol while taking metronidazole. If you are taking this medication, wait until at least one day after finishing metronidazole treatment before drinking alcohol.

Blood cell counts: This medication may cause low white blood cell counts, which can mean your immune system is weak. If you develop a fever, talk to your doctor as soon as possible. Your doctor may also perform blood tests regularly to monitor your blood cell counts if you are taking this medication for a long period of time.

Confusion/dizziness: This medication may cause confusion or dizziness. Avoid driving or other tasks requiring alertness if the medication affects you in this way.

Diarrhea: If diarrhea occurs while taking metronidazole,contact your doctor.

Liver disease:. If you have liver problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking this medication.

Neurological side effects: Stop treatment with metronidazole and see your doctor if muscle incoordination, seizures, or numbness or tingling in the hands or feet occur.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: Metronidazole passes into breast milk. It should not be taken by women who are breast-feeding.

Children: The safety and effectiveness of using this medication have not been established for children.

What other drugs could interact with Flagyl?

There may be an interaction between metronidazole and any of the following:

  • 5-fluorouracil
  • alcohol
  • alfuzosin
  • amiodarone
  • aripirazole
  • barbiturates (e.g., phenobarbital, primidone, butalbital)
  • budesonside
  • busulfan
  • bosutinib
  • disulfiram
  • colchicine
  • cyclosporine
  • eplerenone
  • everolimus
  • fentanyl
  • ivacaftor
  • lithium
  • lurasidone
  • mebendazole
  • phenytoin
  • pimozide
  • sodium picosulfate
  • tolvaptan
  • typhoid vaccine (live)
  • vecuronium
  • warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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