September 17, 2014
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Jurnista

(hydromorphone controlled-release)

DIN (Drug Identification Number)

02337266 JURNISTA 4MG EXTENDED-RELEASE TABLET
02337274 JURNISTA 8MG EXTENDED-RELEASE TABLET
02337282 JURNISTA 16MG EXTENDED-RELEASE TABLET
02337290 JURNISTA 32MG EXTENDED-RELEASE TABLET

How does Jurnista work? What will it do for me?

Hydromorphone controlled-release belongs to the family of medications known as opioid analgesics (narcotic pain relievers). It is used to treat chronic, severe pain. Hydromorphone works on the brain to increase the ability to tolerate pain. Hydromorphone controlled-release works by gradually releasing the medication into the body to help control pain that requires the prolonged or continuous use of an opioid pain killer.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Jurnista?

[Jurnista]

For people who are not currently taking other opioid pain medications or are taking low doses of weak opioid medications, the usual adult dose of hydromorphone controlled-release tablets is 4 mg every 24 hours.

For people who are receiving other formulations of hydromorphone or other opioid medications, the dose depends on the dose of these medications that you are currently taking. Your doctor will determine the dose that is appropriate for you.

Your doctor can adjust your dose every 48 hours until a dose that controls your pain with tolerable side effects is reached.

Your daily dose should be taken once every 24 hours. Swallow hydromorphone controlled-release tablets whole. Do not chew, crush, dissolve, or break the contents of the tablet, as this could result in too much hydromorphone being released rapidly and could be fatal.

You may notice what appears to be a tablet in your stool. This is normal and occurs because the tablet does not completely dissolve after all the medication has been released in the body.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Jurnista come in?

Jurnista

4 mg
Each pale beige, round, biconvex, prolonged-release tablet, with "HM 4" printed in black ink on one side, contains 4.36 mg and delivers 4 mg hydromorphone HCl, equivalent to 3.56 mg hydromorphone base. Nonmedicinal ingredients: butyl hydroxytoluene, cellulose acetate, ferric oxide red, ferric oxide yellow, hypromellose, iron oxide black, lactose anhydrous, macrogol, magnesium stearate, polyethylene oxide, povidone, propylene glycol, sodium chloride, and titanium dioxide. May contain traces of sodium metabisulfite.

8 mg
Each red, round, biconvex, prolonged-release tablet, with "HM 8" printed in black ink on one side, contains 8.72 mg and delivers 8 mg hydromorphone HCl, equivalent to 7.12 mg hydromorphone base. Nonmedicinal ingredients: butyl hydroxytoluene, cellulose acetate, ferric oxide red, glycerol triacetate, hypromellose, iron oxide black, lactose anhydrous, lactose monohydrate, macrogol, magnesium stearate, polyethylene oxide, povidone, propylene glycol, sodium chloride, and titanium dioxide. May contain traces of sodium metabisulfite.

16 mg
Each yellow, round, biconvex, prolonged-release tablet, with "HM 16" printed in black ink on one side, contains 16.35 mg and delivers 16 mg hydromorphone HCl, equivalent to 14.24 mg of hydromorphone base. Nonmedicinal ingredients: butyl hydroxytoluene, cellulose acetate, ferric oxide yellow, glycerol triacetate, hypromellose, iron oxide black, lactose anhydrous, lactose monohydrate, macrogol, magnesium stearate, polyethylene oxide, povidone, propylene glycol, sodium chloride, and titanium dioxide. May contain traces of sodium metabisulfite.

32 mg
Each white, round, biconvex, prolonged-release tablet, with "HM 32" printed in black ink on one side, contains and delivers 32.00 mg hydromorphone HCl, equivalent to 28.48 mg of hydromorphone base. Nonmedicinal ingredients: butyl hydroxytoluene, cellulose acetate, ferric oxide yellow, glycerol triacetate, hypromellose, iron oxide black, lactose anhydrous, lactose monohydrate, macrogol, magnesium stearate, polyethylene oxide, povidone, propylene glycol, sodium chloride, and titanium dioxide. May contain traces of sodium metabisulfite.

Who should NOT take Jurnista?

Do not take this medication if you:

  • are allergic to hydromorphone, other opioid (narcotic) pain medications (e.g., morphine, codeine, oxycodone) or to any of the ingredients of the medication
  • are taking or have taken (within the last 14 days) MAO inhibitors (e.g., phenelzine, tranylcypromine)
  • have had surgery or have an underlying condition that may cause narrowing or obstruction of the intestines
  • have acute alcoholism
  • have acute asthma or other obstructive lung disease
  • have acute pain, or pain following surgery
  • have acute respiratory depression (slowed breathing)
  • have a head injury
  • have convulsions or seizure disorders
  • have cor pulmonale (heart failure caused by chronic high blood pressure in the arteries of the lungs)
  • have delirium tremens (e.g., confusion, diarrhea, shaking, fever, hallucinations, disorientation) associated with alcohol withdrawal
  • have increased carbon dioxide levels in the blood
  • have increased intracranial pressure (increased pressure inside the head), cerebrospinal pressure, or head injury
  • have mild or intermittent pain that can otherwise be managed
  • have pulmonary edema (fluid build-up in the lungs)
  • have severe central nervous system (CNS) depression (slowed nervous system)
  • have or may have surgical abdomen (e.g., paralytic ileus)
  • are pregnant, in labour or delivering, or breastfeeding

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