September 20, 2014
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Drug Factsheets

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Apo-Naproxen SR

(naproxen controlled-release)

DIN (Drug Identification Number)

02177072 APO-NAPROXEN SR TABLETS 750MG

How does Apo-Naproxen SR work? What will it do for me?

Naproxen controlled-release belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce the pain and swelling associated with rheumatoid arthritis and osteoarthritis. It works by reducing the amount of certain chemicals produced by your body that cause pain and swelling.

Naproxen controlled-release does not cure these conditions nor does it prevent these conditions from getting worse. The full effects of this medication are usually seen within 1 or 2 weeks.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Apo-Naproxen SR?

The recommended starting dose of naproxen controlled-release is 750 mg taken once daily.

Your doctor may adjust your dose according to your response. The maximum daily dose is 1,500 mg. The lowest dose needed to control pain and inflammation should be used.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Naproxen controlled-release is best taken after a meal, or with food or milk. Do not lie down for about 15 minutes to 30 minutes after taking this medication. Swallow the tablets whole, and do not crush or chew them.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Apo-Naproxen SR come in?

This medication is available as a 750 mg controlled-release tablet.

Who should NOT take Apo-Naproxen SR?

Do not take this medication if you:

  • are allergic to naproxen or any ingredients of the medication
  • are breast-feeding
  • are in the third trimester of pregnancy (after 28 weeks of pregnancy)
  • are under 18 years of age
  • have a bleeding disorder
  • have a history of asthma, itchy skin rash, or allergic reactions after taking ASA (acetylsalicylic acid) or other nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., ibuprofen, celecoxib, diclofenac, indomethacin, etc.)
  • have active stomach bleeding such as gastric or duodenal ulcer, or have other types of bleeding from the stomach or intestines
  • have bleeding in the brain
  • have high blood potassium (hyperkalemia)
  • have or have had inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis)
  • have recently had heart bypass surgery
  • have severe, uncontrolled heart failure
  • have severely decreased liver function or active liver disease
  • have severely decreased kidney function or worsening kidney disease

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