August 27, 2014
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Vimovo

(esomeprazole - naproxen)

DIN (Drug Identification Number)

02361701 VIMOVO 375/20MG MODIFIED RELEASE TABLET
02361728 VIMOVO 500/20MG MODIFIED RELEASE TABLET

How does Vimovo work? What will it do for me?

This is a combination medication that contains esomeprazole and naproxen. Esomeprazole belongs to the class of medications called proton pump inhibitors and naproxen belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs).

This combination medication is used to treat signs and symptoms of osteoarthritis (OA), rheumatoid arthritis (RA), and ankylosing spondylitis (long-term inflammation disease of the joints), and to decrease the risk of developing stomach ulcers in people at risk for developing stomach ulcers due to NSAIDs.

Esomeprazole works by reducing the amount of acid that stomach produces.

Naproxen relieves pain and reduces swelling and inflammation by reducing a substance in the body that leads to inflammation and pain. If immediate relief of pain is desired, esomeprazole - naproxen should not be used as it releases medication over a longer period of time.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Vimovo?

The recommended daily dose of esomeprazole - naproxen is one 375/20 mg tablet twice daily or one 500/20 mg tablet twice daily. Esomeprazole - naproxen should be taken at least 30 minutes before meals. You should swallow esomeprazole - naproxen tablet whole with water. It should not be split, chewed, or crushed.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Vimovo come in?

375/20 mg
Each yellow, oval, film-coated tablet printed "375/20" in black ink on one side contains 20 mg esomeprazole and 375 mg naproxen. Nonmedicinal ingredients: carnauba wax, croscarmellose sodium, glycerol monostearate, hypromellose, iron oxide black, iron oxide yellow, macrogols, magnesium stearate, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion, methyl parahydroxybenzoate, polydextrose, polysorbate, povidone, propylene glycol, propyl parahydroxybenzoate, silica colloidal anhydrous, titanium dioxide, and triethyl citrate.

500/20 mg
Each yellow, oval, film-coated tablet printed "500/20" in black ink on one side contains 20 mg esomeprazole and 500 mg naproxen. Nonmedicinal ingredients: carnauba wax, croscarmellose sodium, glycerol monostearate, hypromellose, iron oxide black, iron oxide yellow, macrogols, magnesium stearate, methacrylic acid-ethyl acrylate copolymer (1:1) dispersion, methyl parahydroxybenzoate, polydextrose, polysorbate, povidone, propylene glycol, propyl parahydroxybenzoate, silica colloidal anhydrous, titanium dioxide, and triethyl citrate.

Who should NOT take Vimovo?

Do not take this medication if you:

  • are allergic to naproxen, esomeprazole, or any ingredients of this medication
  • are 18 years of age or younger
  • are breast-feeding
  • are in the third trimester of pregnancy
  • have a bleeding disorder including bleeding in the brain
  • have an active ulcer or bleeding in the stomach or intestines
  • have a history of asthma or allergic-type reactions after taking ASA or other NSAIDs (i.e., complete or partial syndrome of ASA-intolerance-rhinosinusitis, hives, swelling of the skin, or sac-like growths of the inflamed nose tissue)
  • have high blood potassium
  • have inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis)
  • have scheduled heart bypass surgery or have recently had this surgery
  • have severe kidney disease
  • have severe untreated heart failure
  • have severely impaired liver function or active liver disease

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