April 23, 2014
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Drug Factsheets

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Bonamine

(meclizine)

DIN (Drug Identification Number)

00220442 BONAMINE 25MG CHEWABLE TABLET

What side effects are possible with Bonamine?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • blurred or double vision
  • change in appetite (increase or decrease)
  • constipation
  • diarrhea
  • dizziness
  • drowsiness
  • dry mouth, nose, and throat
  • fatigue
  • headache
  • nausea
  • nervousness
  • skin rash
  • trouble sleeping
  • upset stomach
  • vomiting
  • weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blurred vision
  • confusion
  • difficult or painful urination
  • hallucinations (seeing or hearing things that are not there)
  • increased sensitivity to heat
  • rapid, pounding heartbeat
  • signs of liver problems, e.g.:
    • dark urine
    • diarrhea
    • loss of appetite
    • nausea
    • pale stools
    • vomiting
    • weight loss
    • yellowing of the skin or whites of the eyes
  • sore throat
  • thickened mucous from the lungs

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction, e.g.:
    • abdominal cramps
    • difficulty breathing
    • nausea and vomiting
    • swelling of the face and throat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Bonamine?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Asthma: Meclizine causes thickening of the mucous in the lungs and may cause the muscles in the lungs to spasm, causing asthma symptoms to worsen. People with asthma or other breathing problems should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Drowsiness/reduced alertness: This medication may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how this medication affects you.

Enlarged Prostate: Meclizine may make the symptoms of an enlarged prostate worse. People with prostate problems should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Glaucoma: Meclizine may make glaucoma symptoms worse. People with narrow-angle glaucoma should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Pregnancy: Studies on the use of meclizine by women experiencing nausea and vomiting during pregnancy have revealed no evidence of any birth defects caused by the medication. However, this medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: Meclizine may reduce the quantity of breast milk produced by a small degree. It should be used while nursing only if the potential benefits outweigh the risks.

Children: The safety and effectiveness of using this medication have not been established for children under the age of 12. Meclizine has been known to cause hyperexcitability when used by children.

What other drugs could interact with Bonamine?

There may be an interaction between meclizine and any of the following:

  • acetylcholinesterase inhibitors (e.g., donepezil, galantamine, rivastigmine)
  • alcohol
  • antihistamines (e.g., cetirizine, dimenhydrinate, diphenhydramine, hydroxyzine)
  • antipsychotics (e.g., haloperidol, quetiapine, olanzapine, risperidone)
  • barbiturates (e.g., butalbital, phenobarbital)
  • benzodiazepines (e.g., lorazepam, diazepam)
  • benztropine
  • bupropion
  • buspirone
  • butorphanol
  • carbamazepine
  • chloral hydrate
  • cyclobenzaprine
  • entacapone
  • dextroamphetamine
  • gabapentin
  • ipratropium
  • MAO inhibitors (e.g., moclobemide, phenelzine, tranylcypromine)
  • methocarbamol
  • narcotic pain relievers (e.g., codeine, fentanyl, morphine)
  • oxybutynin
  • scopolamine
  • selective serotonin reuptake inhibitors (e.g., citalopram, fluoxetine, sertraline)
  • St. John's wort
  • tramadol
  • tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine)
  • vigabatrin
  • zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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