July 24, 2014
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Drug Factsheets

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Pico-Salax

(picosulfate sodium - magnesium oxide - citric acid)

DIN (Drug Identification Number)

02254794 PICO-SALAX POWDER FOR SOLUTION

What side effects are possible with Pico-Salax?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abdominal pain
  • allergic reaction or hypersensitivity (e.g., rash, hives, or itching)
  • anal pain
  • changes in electrolyte balance (e.g., numbness, skin tingling, muscle spasms, rapid heartbeat, muscle weakness, tremors)
  • diarrhea
  • headache
  • confusion
  • nausea
  • seizures (convulsions)
  • vomiting

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Pico-Salax?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Electrolyte imbalance and water intake: This medication can upset the balance of electrolytes in the body, especially if you are not drinking enough water after each dose. Make sure you follow the directions on how much water to drink after each dose of this medication.

If you have a history of electrolyte imbalance such as hyponatremia (low blood sodium) or hypokalemia (low blood potassium) or if you are taking medications that increase the risk of electrolyte abnormalities (e.g., diuretics), discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Heart disease: If you have heart disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Inflammatory bowel disease: If you have inflammatory bowel disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney disease: If you have kidney disease, your doctor may monitor your blood magnesium levels because this medication may increase the amount of magnesium in the blood. Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Prolonged use: Do not use this medication for more than 24 hours. Using it for a longer period of time than recommended increases the risk of dehydration and electrolyte imbalances.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: It is not known if this medication passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication has not been established for children less than 1 year of age.

Seniors: Seniors are at higher risk of becoming dehydrated. You should make sure you drink enough water while taking this medication.

What other drugs could interact with Pico-Salax?

There may be an interaction between picosulfate sodium - magnesium oxide - citric acid and any of the following:

  • antibiotics (e.g., amoxicillin, penicillin)
  • antidiabetics (e.g., metformin, glyburide)
  • antiepileptics (e.g., carbamazepine, phenytoin)
  • antipsychotic medications (e.g., clozapine, quetiapine)
  • bulk-forming laxatives (e.g., psyllium)
  • iron preparations and supplements
  • medications taken by mouth
  • medications that affect water or electrolyte balance (e.g., diuretics, corticosteroids)
  • medications that cause constipation (e.g., opioids, cholinergics)
  • nonsteroidal anti-inflammatory medications (NSAIDs; e.g., ibuprofen, naproxen)
  • oral contraceptives
  • selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, sertraline)
  • tricyclic antidepressants (e.g., amitriptyline, doxepin)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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