April 19, 2014
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Drug Factsheets

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Peglyte

(polyethylene glycol 3350 - electrolytes)

DIN (Drug Identification Number)

00777838 PEGLITE POWDER FOR SOLUTION
00777846 PEGLYTE SOLUTION

What side effects are possible with Peglyte?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal cramps
  • anal irritation
  • bloating
  • diarrhea and excessive stool frequency
  • feeling of fullness
  • gas
  • nausea
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • hives
  • dermatitis (inflammation of the skin)
  • runny nose

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • seizure

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Peglyte?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Electrolyte imbalance: This medication can upset the balance of electrolytes in the body. If you have a history of electrolyte imbalance such as hyponatremia (low blood sodium) or hypokalemia (low blood potassium) or if you are taking medications that increase the risk of electrolyte abnormalities (e.g., diuretics), discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Frequent or prolonged use: Use this medication only when you need it or as recommended by your doctor. Avoid using this medication repeatedly at short intervals, and do not use it for more than 1 week unless directed by your doctor. Frequent and long-term use of this medication can lead to your body depending on this medication for bowel movements.

Inflammatory bowel disease: If you have an inflammatory bowel disease such as ulcerative colitis or Crohn's disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney disease: If you have kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Nausea, vomiting, and abdominal pain: If you have abdominal pain, nausea, or vomiting, do not take this medication. Talk to your pharmacist or doctor for advice.

Regurgitation/aspiration of medication: If you have an impaired gag reflex or are not fully conscious, you may need to be monitored while using this medication because you may be at risk of regurgitation or aspiration (breathing the solution into the lungs).

Seizure: Seizures have been reported in people using polyethylene glycol-based colon preparations. If you have a seizure disorder or a history of seizures, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication may pass into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication has not been established for children.

Seniors: Seniors with heart disease and kidney disease should be monitored by their doctor if they take this medication. Talk to your doctor how this medication may affect you and whether any special monitoring is needed.

What other drugs could interact with Peglyte?

Medications taken by mouth within 2 hours of starting polyethylene glycol 3350 - electrolytes may be flushed from the body and not absorbed. If you are taking medications, speak with your doctor or pharmacist.

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

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