October 31, 2014
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Drug Factsheets

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Fampyra

(fampridine)

DIN (Drug Identification Number)

02379910 FAMPYRA 10MG TABLET

How does Fampyra work? What will it do for me?

Fampridine belongs to the class of medications called potassium channel blockers. Fampridine is used to improve walking in adults with multiple sclerosis (MS) related walking difficulties. It is believed to work by improving the movement of messages through the nerves.

If there is no improvement in the symptoms of walking disability after 4 weeks, this medication should not be continued.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Fampyra?

The recommended dose of fampridine is 10 mg taken twice daily, one tablet in the morning and one tablet in the evening. The doses should be taken 12 hours apart.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Fampridine should be swallowed whole with a glass of water. Do not crush, dissolve, divide, or chew the tablet, as this causes an increase in the amount of medication released at once and will increase the risk of seizures. Take fampridine without food.

It is important that this medication be taken exactly as prescribed by your doctor. Taking more than the recommended dose increases the risk of seizures.

If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, in the original container to protect it from light and moisture. Keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Fampyra come in?

Each film-coated, white to off-white, biconvex, oval shaped, non-scored, sustained release tablet with a flat edge and debossed with "A10" on one side, contains 10 mg fampridine. Non-medicinal ingredients: hydroxypropyl methylcellulose USP, microcrystalline cellulose USP, colloidal silicon dioxide NF, magnesium stearate USP, hydroxypropyl methylcellulose/hypromellose USP, titanium dioxide USP, and macrogol/PEG 400 NF.

Who should NOT take Fampyra?

Do not take fampridine if you:

  • are allergic to fampridine or any ingredients of the medication
  • are taking other forms of fampridine or 4-aminopyridine
  • have reduced kidney function
  • have or have had seizures
  • are taking cimetidine or quinidine

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