August 27, 2014
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Zocor

(simvastatin)

DIN (Drug Identification Number)

00884332 ZOCOR 10MG TABLET
00884340 ZOCOR 20MG TABLET
00884359 ZOCOR 40MG TABLET
00884324 ZOCOR 5MG TABLET
02240332 ZOCOR 80MG TABLET

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How does Zocor work? What will it do for me?

Simvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins"). It is used in addition to diet and exercise to lower cholesterol levels.

It is also used to decrease the risk of heart attack, stroke, or death regardless of whether cholesterol levels are high or not for people who have coronary heart disease (CHD) or have other arteries in the body that are blocked, or for those who have diabetes and are over the age of 40.

It works by blocking an enzyme that helps create cholesterol in the body. Therefore, less cholesterol is made and levels of cholesterol in the blood decrease. Simvastatin lowers the level of total cholesterol and low density lipoprotein (LDL, or "bad" cholesterol) and raises high density lipoprotein (HDL, or "good" cholesterol) levels.

The medication usually takes about 2 to 4 weeks to have a significant effect on the cholesterol level in your blood. After this time, your doctor will likely send you for a blood test to check for changes in your cholesterol levels.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Zocor?

Before or when starting simvastatin, you should be placed on a cholesterol-lowering diet. If appropriate, a health care professional will discuss an individualized program of weight control and physical exercise with you.

The starting dose of this medication depends on your medical conditions and other medications you are taking, and can range from 5 mg to 40 mg taken once daily in the evening. The maximum recommended daily dose is 80 mg, which may be required for some people who are unable to achieve a desired cholesterol level using lower doses. The maximum daily dose may be lower for people taking certain medications.

The maximum dose for children and adolescents 10 to 17 years of age is 40 mg.

For best results in lowering your cholesterol, it is very important that you closely follow the diet suggested by your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children.

This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Zocor come in?

5 mg
Each buff-coloured, oval-shaped, biconvex, film-coated tablet, engraved "MSD 726" on one side and "ZOCOR 5" on the other, contains 5 mg of simvastatin. Nonmedicinal ingredients: ascorbic acid, butylated hydroxyanisole, citric acid monohydrate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, talc, titanium dioxide, and yellow ferric oxide.

10 mg
Each peach-coloured, oval-shaped, biconvex, film-coated tablet, engraved "MSD 735" on one side and plain on the other, contains 10 mg of simvastatin. Nonmedicinal ingredients: ascorbic acid, butylated hydroxyanisole, citric acid monohydrate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, red ferric oxide, talc, titanium dioxide, and yellow ferric oxide.

20 mg
Each tan-coloured, oval-shaped, biconvex, film-coated tablet, engraved "MSD 740" on one side and plain on the other, contains 20 mg of simvastatin. Nonmedicinal ingredients: ascorbic acid, butylated hydroxyanisole, citric acid monohydrate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, red ferric oxide, talc, titanium dioxide, and yellow ferric oxide.

40 mg
Each brick-red-coloured, oval-shaped, biconvex, film-coated tablet, engraved "MSD 749" on one side and plain on the other, contains 40 mg of simvastatin. Nonmedicinal ingredients: ascorbic acid, butylated hydroxyanisole, citric acid monohydrate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, red ferric oxide, talc, and titanium dioxide.

80 mg
Each brick-red-coloured, capsule-shaped, film-coated tablet, engraved "543" on one side and "80" on the other, contains 80 mg of simvastatin. Nonmedicinal ingredients: ascorbic acid, butylated hydroxyanisole, citric acid monohydrate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, pregelatinized starch, red ferric oxide, talc, and titanium dioxide.

Who should NOT take Zocor?

Simvastatin should not be taken by anyone who:

  • is allergic to simvastatin or to any of the ingredients of the medication
  • is breast-feeding
  • is pregnant or plans to become pregnant
  • has active liver disease or unexplained increases in liver function tests

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