April 23, 2014
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Drug Factsheets

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Nitrol

(nitroglycerin ointment)

DIN (Drug Identification Number)

01926454 NITROL OINTMENT 2%

How does Nitrol work? What will it do for me?

Nitroglycerin belongs to the class of medications called antianginals. Nitroglycerin ointment is used to prevent angina attacks (chest pain). Nitroglycerin reduces the number of angina attacks by relaxing blood vessels and increasing the oxygen and blood supply to the heart. Nitroglycerin ointment is not intended for immediate relief of angina.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are being given this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use Nitrol?

Nitroglycerin ointment may be applied every 3 to 8 hours if necessary, but one application at bedtime is often sufficient for the entire night. The usual dose is 2.5 cm to 5 cm as squeezed from the tube onto the applicator.

You may use the ointment on any convenient skin area - many people prefer to apply it to the chest. Place the applicator with the ointment side down onto the desired area. Spread the ointment over at least a 5 cm by 7.5 cm area in a thin, uniform layer. Cover the ointment with the supplied paper, plastic kitchen wrap, or other suitable material. This can be held in place with adhesive or transparent tape.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are applying the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, apply it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Nitrol come in?

Each tube of ointment contains 2% nitroglycerin. Nonmedicinal ingredients: lactose, lanolin, petrolatum, and purified water (all USP standard).

Who should NOT take Nitrol?

Nitroglycerin ointment should not be used by anyone who:

  • is allergic or sensitive to nitroglycerin or to any of the ingredients of the medication
  • is allergic or sensitive to any organic nitrates
  • is taking erectile dysfunction medications called PDE-5 inhibitors (e.g., sildenafil, tadalafil, vardenafil)
  • has extremely low blood pressure
  • has increased eye pressure (glaucoma)
  • has increased pressure within the head (e.g., after an accident)
  • has severe anemia

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