October 31, 2014
ABCDEFGHIJKLMNOPQRSTUVWXYZ

Drug Factsheets

 Health Home >> Medications 

Salofalk

(5-aminosalicylic acid (mesalamine, mesalazine))

DIN (Drug Identification Number)

02242146 SALOFALK 1000 MG SUPPOSITORIES
02112795 SALOFALK 2G/60G RECTAL SUSPENSION
02112809 SALOFALK 4G/60G RECTAL SUSPENSION
02112760 SALOFALK 500MG SUPPOSITORIES
02112787 SALOFALK 500MG ENTERIC-COATED TABLET

What side effects are possible with Salofalk?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal or stomach cramps or pain (mild)
  • back or joint pain
  • diarrhea (mild)
  • dizziness
  • fatigue
  • flu-like symptoms (sudden lack of energy, fever, cough, sore throat)
  • gas
  • headache (mild)
  • heartburn or indigestion
  • increased frequency of bowel movements
  • loss of appetite
  • loss of hair
  • nausea or vomiting

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • anxiety
  • fast heartbeat
  • mood swings
  • severe back or stomach pain
  • severe headache
  • signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)
  • skin rash and itching
  • unusual tiredness or weakness

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (i.e., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of acute intolerance syndrome (e.g., abdominal or stomach cramps or pain [severe], bloody diarrhea, chills, fever)
  • signs of heart attack (e.g., chest pain, possibly moving to the left arm, neck, or shoulder)
  • signs of inflammation around the heart (e.g., fatigue, fever, difficulty breathing, cough)
  • signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, fever, chills, rapid heartbeat, swollen abdomen)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Salofalk?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Acute intolerance syndrome: This medication has been known to cause symptoms similar to those of worsening Crohn's disease or ulcerative colitis. If you experience the sudden onset of symptoms such as cramping, acute abdominal pain and bloody diarrhea, headache, rash, and possibly fever, contact your doctor immediately.

Allergy: Some people who are allergic to sulfasalazine or acetylsalicylic acid (ASA) also experience allergic reactions to mesalamine (5-ASA). Before you take 5-ASA, inform your doctor about any previous adverse reactions you have had to medications, especially sulfasalazine or ASA.

Contact your doctor at once if you experience signs of an allergic reaction such as skin rash, itching, difficulty breathing or swelling of the face and throat.

Heart problems: People with heart problems may be at an increased risk of side effects of 5-ASA. If you have heart problems or a history of heart problems, including heart infections, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney function: This medication is removed from the body by the kidneys. 5-ASA may not be removed from the body as quickly as expected if your kidneys are not working properly. This increases the likelihood of experiencing side effects.

If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Liver function: The use of this medication by people with reduced liver function has not been well studied. If you have reduced liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor as soon as possible.

Slow stomach emptying: The tablet form of 5-ASA may not work as well for people with a condition known as pyloric stenosis. If you have pyloric stenosis or have a history of slow emptying of the stomach, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Tablets in stool: Infrequently, what looks to be intact or partially intact tablets may appear in the stool. If this occurs repeatedly, consult your doctor.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking 5-aminosalicylic acid, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of this medication for use by children have not been established.

What other drugs could interact with Salofalk?

There may be an interaction between 5-aminosalicylic acid and any of the following:

  • 6-mercaptopurine
  • antacids (e.g., aluminum hydroxide, calcium carbonate, sodium bicarbonate)
  • azathioprine
  • digoxin
  • furosemide
  • H2 antagonists (e.g., cimetidine, famotidine, ranitidine)
  • lactulose
  • methotrexate
  • nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., naproxen, ibuprofen)
  • probenecid
  • proton pump inhibitors (e.g., esomeprazole, lansoprazole, omeprazole, pantoprazole)
  • spironolactone
  • sulfinpyrazone
  • sulfonylureas (e.g., glyburide, gliclazide)
  • thioguanine
  • varicella (chicken pox) vaccine
  • warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Previous | 1 | 2 | 


Did you find what you were looking for on our website? Please let us know.

Ad

The contents of this site are for informational purposes only and are meant to be discussed with your physician or other qualified health care professional before being acted on. Never disregard any advice given to you by your doctor or other qualified health care professional. Always seek the advice of a physician or other licensed health care professional regarding any questions you have about your medical condition(s) and treatment(s). This site is not a substitute for medical advice.

© 1996 - 2014 MediResource Inc. - MediResource reaches millions of Canadians each year.