October 22, 2014
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Drug Factsheets

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Retin-A

(tretinoin (acne))

DIN (Drug Identification Number)

00897329 RETIN-A 0.01% CREAM
00870013 RETIN-A 0.01% GEL
00897310 RETIN-A 0.025% CREAM
00443816 RETIN-A 0.025% GEL
00443794 RETIN-A 0.05% CREAM
00870021 RETIN-A 0.1% CREAM

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How does Retin-A work? What will it do for me?

Tretinoin is used to treat certain types of acne. Tretinoin works by causing the skin's outer layer to grow more quickly and be replaced with new skin cells, which helps to reduce the formation of blackheads, whiteheads, and other acne lesions. It may take several weeks to see improvement in your acne and the full effect of this medication may not be seen for 8 – 10 weeks.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

How should I use Retin-A?

Tretinoin should be applied once daily at bedtime to lightly cover the areas being treated. The area of application should be thoroughly cleansed with a mild soap and water and patted dry with a soft towel. Apply a small amount (about the size of a pea) on your fingertip and spread it on the skin where acne lesions appear. Use only enough medication to cover the affected areas lightly. Avoid rubbing the medication into the skin.

Keep the medication away from the corners of the nose, mouth, eyes, and easily irritated areas. Avoid applying excess amounts as the medication may run into the eyes and other areas that should be avoided. Tretinoin should not be applied to areas of the skin where you have other problems such as eczema, severely inflamed skin, or open skin lesions. After you wash your skin in the morning, it is recommended that you apply a moisturizer or a moisturizer with sunscreen that will not aggravate your acne.

After 3 to 6 weeks of treatment, you may notice new blemishes. Keep using this medication as you will notice a gradual improvement over 8 - 10 weeks.

Prolonged exposure to sunlight, sunlamps, wind, and cold should be avoided during treatment. If exposure to the sun is unavoidable, use a sunscreen with minimum SPF 15 and wear protective clothing.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important that this medication be applied exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature and keep it out of the reach of children. Gel products are flammable and should be kept away from heat of flame.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.





What form(s) does Retin-A come in?

Cream

0.01%
Each gram of cream contains 0.01% tretinoin in a bland, hydrophilic base. Nonmedicinal ingredients: butylated hydroxytoluene, isopropyl myristate, polyoxyl (40) stearate, purified water, sorbic acid, stearic acid, stearyl alcohol, and xanthan gum.

0.025%
Each gram of cream contains 0.025% tretinoin in a bland, hydrophilic base. Nonmedicinal ingredients: butylated hydroxytoluene, isopropyl myristate, polyoxyl (40) stearate, purified water, sorbic acid, stearic acid, stearyl alcohol, and xanthan gum.

0.05%
Each gram of cream contains 0.05% tretinoin in a bland, hydrophilic base. Nonmedicinal ingredients: butylated hydroxytoluene, isopropyl myristate, polyoxyl (40) stearate, purified water, sorbic acid, stearic acid, stearyl alcohol, and xanthan gum.

0.1%
Each gram of cream contains 0.1% tretinoin in a bland, hydrophilic base. Nonmedicinal ingredients: butylated hydroxytoluene, isopropyl myristate, polyoxyl (40) stearate, purified water, sorbic acid, stearic acid, stearyl alcohol, and xanthan gum.

Gel

0.01%
Each gram of gel contains 0.01% tretinoin. Nonmedicinal ingredients: butylated hydroxytoluene, undenatured ethanol, and hydroxypropyl cellulose.

0.025%
Each gram of gel contains 0.025% tretinoin. Nonmedicinal ingredients: butylated hydroxytoluene, undenatured ethanol, and hydroxypropyl cellulose.

Who should NOT take Retin-A?

Do not use this medication if you are allergic to tretinoin or any ingredients of the medication.

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