April 17, 2014
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Drug Factsheets

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Androcur

(cyproterone acetate)

DIN (Drug Identification Number)

00704431 ANDROCUR 50MG TABLET

What side effects are possible with Androcur?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • changes in walking and balance (clumsiness or unsteadiness)
  • hair loss
  • impotence
  • inability to move legs or arms
  • increase in bowel movements and loose stools
  • increased sensitivity of skin to sunlight
  • loss of strength or energy
  • reduced (or increased) sexual interest
  • skin bleeding, blistering, coldness, or discoloration
  • swelling of the breasts or breast soreness
  • unusual increase in hair growth
  • weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abdominal pain or tenderness
  • back pain
  • blisters
  • blurred vision
  • chest pain
  • chills
  • clay coloured stools
  • confusion
  • cough
  • depression
  • dizziness
  • drowsiness
  • dry mouth
  • fainting or light-headedness when getting up
  • fast heartbeat
  • hallucinations
  • hives
  • increase in blood pressure
  • increase in hunger and/or thirst
  • lower back or side pain
  • nausea and vomiting
  • painful or difficult urination
  • red, thickened or scaly skin
  • shortness of breath
  • skin rash
  • sore throat
  • sores, ulcers, or white spots on lips or in mouth
  • stiff neck
  • stomach ache
  • swollen and painful glands
  • tightness in chest
  • unexplained weight loss
  • unusual bleeding or bruising
  • vision changes
  • wheezing
  • yellow eyes or skin

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • bloody or black, tarry stools or blood in urine
  • difficulty breathing or shortness of breath
  • irregular breathing
  • pains in chest, groin, or legs, especially calves of legs
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • seizures
  • sudden and severe weakness in arm and/or leg on one side of the body
  • sudden loss of coordination
  • sudden slurred speech
  • temporary blindness

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Androcur?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Alcohol: The effectiveness of cyproterone may be reduced if you consume alcohol. You should limit the amount of alcohol you drink when taking this medication.

Depression: Cyproterone use has occasionally been associated with an increased incidence of depressive mood changes, especially with start of therapy. You should notify your doctor if you've had depression in the past.

Diabetes: Cyproterone may cause blood glucose levels to increase if you have diabetes mellitus.

Heart disease: Cyproterone can cause fluid to accumulate in the body. If you have heart disease, be cautious when using this medication because your heart may have to work harder.

Liver disease: Cyproterone can cause damage to the liver. It usually develops after several months of treatment. Your doctor will monitor your liver function with blood tests if there are any symptoms or signs of liver damage.

Pregnancy: Cyproterone is not for use by women.

Breast-feeding: Cyproterone is not for use by women.

Children: Cyproterone is not recommended for use in children.

What other drugs could interact with Androcur?

There may be an interaction between cyproterone and any of the following:

  • ethinyl estradiol
  • testosterone and androgens

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, decongestants, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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