August 22, 2014
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Drug Factsheets

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Imodium

(loperamide)

DIN (Drug Identification Number)

02183862 IMODIUM - CAPLET 2MG
02230542 IMODIUM QUICK DISSOLVE 2MG TABLET
02291800 IMODIUM 2 MG/15 ML ORAL SOLUTION

What side effects are possible with Imodium?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • burning or prickly sensation on the tongue (quick-dissolve tablets)
  • dizziness
  • drowsiness
  • dry mouth
  • gas
  • headache
  • nausea or vomiting
  • tiredness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abdominal or stomach pain, cramps, discomfort, or distention
  • constipation
  • rash

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • symptoms of a severe allergic reaction, e.g.:
    • difficulty breathing
    • hives
    • peeling or blistering skin
    • swelling of the mouth or throat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Imodium?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breastfeeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Acquired immune deficiency syndrome (AIDS): People with AIDS should stop taking loperamide and contact their doctor if they experience abdominal swelling or distention.

Constipation: If you develop constipation, stop taking this medication and contact your doctor.

Drowsiness or dizziness: Loperamide may cause drowsiness or dizziness. Do not drive or operate machinery until you know how loperamide affects you.

Fluids and electrolytes: The loss of fluids and electrolytes (e.g., chloride, sodium) can occur if you have diarrhea. Loperamide helps with the symptoms of diarrhea but will not correct any fluid or electrolyte problems caused by diarrhea. Talk to your doctor or pharmacist about whether you need fluid and electrolyte replacement, also referred to as oral rehydration therapy.

Improvement in diarrhea: If your diarrhea has not improved after 48 hours of treatment with loperamide, stop taking it and contact your doctor.

Liver disease: People with liver disease should be monitored carefully by their doctor while taking this medication.

Medical conditions: Loperamide should not be used by people with intestinal infections such as dysentery, which is often associated with severe diarrhea, fever, and blood in the stool, and other infections of the gut. A more serious problem of the bowel may develop if loperamide is used by some people with acute ulcerative colitis or a serious form of diarrhea associated with antibiotic use.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.

Breast-feeding: This medication passes into breast milk. If you are a breast-feeding mother and are taking loperamide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: This medication is not recommended for use in children under the age of 12 except on the advice of a physician. Loperamide should not be given to children under 6 years of age without medical prescription and supervision. Loperamide tablets are not suitable for children under 6 years of age. Loperamide should not be used for children under 2 years of age. (See "Who should not take this medication.")

What other drugs could interact with Imodium?

There may be an interaction between loperamide and any of the following:

  • alcohol
  • barbiturates (e.g., phenobarbital, butalbital)
  • benzodiazepines (e.g., diazepam, lorazepam)
  • phenothiazines (e.g., perphenazine, fluphenazine)
  • quinidine
  • ritonavir
  • tricyclic antidepressants (e.g., amitriptyline, nortriptyline)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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