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Ovidrel

(choriogonadotropin alpha)

In this factsheet:
• How does Ovidrel work? What will it do for me?
• How should I use Ovidrel?
• What form(s) does Ovidrel come in?
• Who should NOT take Ovidrel?
• What side effects are possible with Ovidrel?
• Are there any other precautions or warnings for Ovidrel?
• What other drugs could interact with Ovidrel?

DIN (Drug Identification Number)

Get ready to talk to your doctor about trying to get pregnant.

Fill out this short doctor discussion guide to help you start the discussion and determine the best approach and next steps for you.

Fertility Doctor Discussion Guide

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Have you been actively trying to get pregnant for twelve months or more? (or six months or more if you're 35 or older) Have you or your partner already been diagnosed with a fertility problem? Have you tried using ovulation predictor kits / BBT charts / other? Would you like to find out more about your treatment options? Do you feel concerned that you have been unsuccessful to date? As a result of your inability to get pregnant, do you find yourself uncomfortable around family or friends with children? Has your inability to get pregnant had a negative effect on your relationship with your partner? Has your inability to get pregnant negatively affected your sexual relationship with your partner? Do your fertility problems get in the way of your work or home life obligations?

YES      NO NOT AT ALL NOT AT ALL

SOMEWHAT SOMEWHAT

QUITE A BIT QUITE A BIT

Now you're ready to talk to your doctor about trying to get pregnant. Just print this sheet and bring it with you to your next doctor's appointment. Also write down any specific questions you have.

Keep in mind that many options are available to help you get pregnant and that you're not alone in your journey. To find out more about fertility, visit the Fertility channel.

How does Ovidrel work? What will it do for me?

Choriogonadotropin alpha belongs to the class of medications called gonadotropins. Choriogonadotropin alpha, or human chorionic gonadotropin (hCG), is used as part of fertility treatment for women with ovarian dysfunction. It helps follicles mature and triggers ovulation (the release of mature eggs from ovaries).

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using this medication, speak to your doctor. Do not stop using this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use Ovidrel?

The usual dose of choriogonadotropin alpha is 250 µg injected under the skin as directed by your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Your doctor or other health care professional will show you exactly how to inject the medication. Inspect the solution carefully before injecting it. Do not use your injectable solution if it appears to contain particles or is not clear.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose of choriogonadotropin alpha, talk to your doctor about when you should receive your next dose.

Store pre-filled syringes at room temperature for up to 30 days or in the refrigerator (2°C to 8°C) until the expiration date. Store pre-filled pens in the refrigerator (2°C to 8°C). Store vials at or below room temperature (25°C). Store in the original package and do not freeze. Protect this medication from light and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does Ovidrel come in?

Pre-filled syringes
Each pre-filled syringe of sterile solution contains 250 µg of choriogonadotropin alpha. Nonmedicinal ingredients: mannitol, phosphoric acid, L-methionine, Poloxamer 188, sodium hydroxide, and water for injection.

Pre-filled pen
Each pre-filled pen of sterile solution contains 250 µg of choriogonadotropin alpha. Nonmedicinal ingredients: mannitol, phosphoric acid, L-methionine, Poloxamer 188, sodium hydroxide, disodium hydrogen phosphate dihydrate, sodium dihydrogen phosphate monohydrate, and water for injection.

Lyophilised powder for reconstitution
Each vial contains 285 µg of choriogonadotropin alpha. Nonmedicinal ingredients: sucrose, phosphoric acid, sodium hydroxide, which, when reconstituted with the diluent, will deliver 250 µg of recombinant human chorionic gonadotrophin.

Who should NOT take Ovidrel?

Do not use choriogonadotropin alpha if you:

• are allergic to choriogonadotropin alpha, hCG preparations, or any ingredients of the medication
• are pregnant
• have abnormal uterine bleeding of unknown cause
• have an ovarian cyst or have an unknown cause of ovarian enlargement
• have an uncontrolled brain lesion (e.g., pituitary tumor)
• have primary ovarian failure
• have sex-hormone (e.g., estrogen) dependent tumours of the reproductive organs or breasts
• have uncontrolled thyroid or adrenal problems

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