April 23, 2014
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Drug Factsheets

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Lipidil EZ

(fenofibrate (crystals))

DIN (Drug Identification Number)

02269082 LIPIDIL EZ 145 MG TABLET
02269074 LIPIDIL EZ 48 MG TABLET

What side effects are possible with Lipidil EZ?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • constipation or diarrhea
  • dizziness
  • fatigue
  • headache
  • nausea
  • red, itchy skin
  • runny nose
  • skin rash
  • stomach pain

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • severe stomach pain, nausea, or vomiting
  • signs of liver problems such as dark urine, general feeling of being unwell, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin
  • unexplained muscle pain, tenderness, weakness, chills, or fever

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.





Are there any other precautions or warnings for Lipidil EZ?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Blood cells: This medication can cause small, temporary decreases in red and white blood cell counts. Your doctor will check for this with blood tests during the first year of treatment.

Combination therapy: The use of fenofibrate and "statin" medications (e.g., atorvastatin, lovastatin, simvastatin) at the same time may increase the risk of side effects. Talk to your doctor about the risks and benefits of taking the two types of medications together.

Gallbladder disease: For some people, fenofibrate (crystals) may cause gallstones. If you experience abdominal or stomach pain, gas, nausea, or bloating (especially after eating high-fat foods), contact your doctor.

Kidney function: People with reduced kidney function may be more at risk of certain side effects when taking fenofibrate (crystals). Depending on the degree of kidney function impairment, lower doses of fenofibrate (crystals) may be needed. People will severely reduced kidney function and those undergoing dialysis treatment should not take this medication.

Liver function: Fenofibrate (crystals) may affect liver function. Your doctor will monitor this with blood tests. People with reduced liver function should not take this medication.

Muscle problems: Treatment with this type of medication has been associated on rare occasions with muscle pain, usually in people with reduced kidney function. Contact your doctor as soon as possible if you notice unexplained muscle pain, tenderness, or weakness, particularly if you have malaise (a general feeling of illness) or fever.

Pancreatitis: An inflammation of the pancreas has been reported with fenofibrates. If you experience severe upper abdominal pain, nausea, or vomiting while taking this medication, contact your doctor immediately.

Pregnancy: This medication should not be used during pregnancy. If you become pregnant while taking this medication, stop taking it and contact your doctor immediately.

Breast-feeding: It is not known if this medication passes into breast milk. This medication should not be used by breast-feeding women.

Children: The safety and effectiveness of using this medication have not been established for children.

Seniors: Seniors are more likely to have reduced kidney function and may need lower doses of this medication.

What other drugs could interact with Lipidil EZ?

There may be an interaction between fenofibrate (crystals) and any of the following:

  • cholestyramine resin
  • colestipol
  • cyclosporine
  • estrogens
  • rosiglitazone
  • "statin" medications (e.g., atorvastatin, lovastatin, simvastatin)
  • warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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